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Comparing two surgical joining techniques after rectal cancer surgery

Compares two bowel-joining methods in adults having rectal cancer surgery, tracking recovery.

Key facts

Who runs it
Bordeaux Colorectal Institute
Where
Montreal and Québec, CanadaSee the 2 sitesAlso in 5 other countries, 13 sites
Trial code
Registry title
Low Powered Colorectal Anastomosis After Rectal Excision (OASIS)
Status
Not yet recruiting
People taking part
400 people, planned
Started
Sept 2025
Expected to end
Sept 2029
Type of study
Observational
Record updated
28 August 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with rectal cancer low in the rectum, without metastasis, who are having keyhole or robotic surgery to remove the rectum with a stapled join (anastomosis) using powered devices.

Age
18 years or older
Sex
All sexes can join.
Disease stage
Rectal cancer lower than 12 cm (4.7 in) from the anal verge, needing a stapled join below 7 cm (2.8 in) from the anal verge, with no metastasis.
Earlier treatment
Can join with or without treatment before surgery (neoadjuvant treatment). Surgery must be keyhole, robotic or TaTME. Can have a temporary ileostomy or not.

Main reasons for not taking part

  • Hand-sewn join (anastomosis)
  • Perforated rectal cancer or pelvic infection before surgery
  • Inflammatory bowel disease
  • Emergency surgery
  • Extended TME or pelvic exenteration

The registry criteria, word for word

Show all 17 criteriaShow less

Who can take part

  • Age ≥ 18
  • Patients with rectal cancer lower than 12 cm from the anal verge requiring either a stapling anastomosis below 7 cm from the anal verge,
  • Patients with powered mechanical anastomosis (INTOCARE devices)
  • Patients with no metastasis
  • Patients operated on by mini-invasive rectal excision (laparoscopic, robotic or TaTME)
  • Patients with or without defunctioning ileostomy
  • Patients with or without neoadjuvant treatment
  • Patient who benefits by medicare system
  • Signed and dated informed consent

Who cannot take part

  • Patients with perforated rectal cancer or preoperative pelvic sepsis
  • Patients with inflammatory bowel disease
  • Patients with handsewn anastomosis
  • Patients operated on in emergency
  • Patients with extended-TME or pelvic exenteration
  • Pregnancy or breast feeding period
  • Legal incapacity or physical, psychological social or geographical status interfering with the patient's ability to agree to participate in the study
  • Persons deprived of liberty or under guardianship

Where in Canada

Also in 5 other countries, 13 sites

  • Hôpital Universitaire McGillMontreal, CanadaContact: Larry LEENo longer taking part
  • CHU de QuebecQuébec, CanadaContact: Francois LETARTENo longer taking part

About the trial

What the trial wants to find out

The objectiive of this prospective, international cohort is to compare two anastomotic techniques (DS vs TTSS) by collecting data during the surgery, and postoperatively (morbidity and functional outcomes).

Read full original descriptionShow less

The choice of technique is left to the discretion of the surgeon based on her/his practices.

The group in the trial

  • Rectal surgery with powered mechanical anastomosis performed with DS or TTSS techniques

    This is an international cohort (France and other international centers) which consists of including patients undergoing rectal surgery with powered mechanical anastomosis performed with DS or TTSS techniques. Surgeons at each center perform one or both techniques. When both types of stapling are possible, the choice of technique is made by the surgeon during the preoperative consultation, in the best interest of the patients, after a case-by-case assessment.

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Low Powered Colorectal Anastomosis After Rectal Excision : An Exploratory, Observational, Prospective, IDEAL Stage 2b International Cohort Study (OASIS)
Plain-language title
Comparing two surgical joining techniques after rectal cancer surgeryGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
28 August 2025