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Compares sex differences in heart upper chamber ablation for atrial fibrillation

Looks at how men and women differ after a first ablation for atrial fibrillation.

Plain-language title generated from the registry record
Registry title: Sex-Based Differences of LA: Impact on AF Ablation.

Key facts

Where
Barcelona, SpainSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults who had a first ablation procedure for atrial fibrillation (paroxysmal or persistent), done by the by-LAWT protocol, with CT and 12-month follow-up data available.

Age
18 years or older
Sex
Men and women can join
Disease stage
Paroxysmal or persistent atrial fibrillation
Earlier treatment
Must have had a first ablation for atrial fibrillation, done according to the by-LAWT protocol. Must not have had any earlier cardiac ablation.

Main reasons for not taking part

  • Under 18 years of age
  • Earlier cardiac ablation of any kind
  • Incomplete procedure or follow-up data
  • Poor quality CT scan before the procedure
  • Structural heart disease that could change atrial size or response to ablation

Read by machine on 9 November 2026.

Where in Spain

  • Teknon Medical centerBarcelona, SpainNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Trial details

Who runs it
Centro Medico Teknon
Trial code
NCT07159685
Record updated
8 September 2025
Original description
The aim of the study is to assess sex-related differences in patients who underwent a first ablation procedure for paroxysmal or persistent AF, guided by the personalized ablation strategy of the BY-LAWT protocol. Specifically, to compare anatomical characteristics, procedural parameters, and clinical outcomes between sexes.Read full original descriptionShow less

Sex-Based Differences of Left Atrium: Impact on Atrial Fibrillation Ablation.

The aim of the study is to assess sex-related differences in patients who underwent a first ablation procedure for paroxysmal or persistent AF, guided by the personalized ablation strategy of the BY-LAWT protocol. Specifically, to compare anatomical characteristics, procedural parameters, and clinical outcomes between sexes.

Inclusion: Patients who underwent a first ablation procedure for atrial fibrillation (paroxysmal or persistent); Availability of an adequate pre-procedural cardiac CT scan for LAWT, LAV and inFAT analysis; Availability of complete procedural data, including ablation index (AI) values recorded using the SmartTouch catheter (Biosense Webster); Availability of 12-month follow-up data for efficacy and safety endpoint evaluation; Ablation performed according to the by-LAWT protocol.

Exclusion: Previous cardiac ablation (including AF ablation or other arrhythmias); Poor quality pre-procedural cardiac MDCT; Structural heart disease (e.g., dilated cardiomyopathy, valvular heart disease with surgical indication) that could substantially influence atrial dimensions or ablation response; Age < 18 years; Incomplete data regarding procedural parameters, or follow-up; Ablation not performed according to the BY-LAWT protocol.

ClinicalTrials.gov NCT07159685