Compares two nutrition supplement formulas in adults with cystic fibrosis
Tests whether one nutrient supplement formula works better than another in adults with cystic fibrosis.
Plain-language title generated from the registry record
Registry title: Nutrition Supplement for Cystic Fibrosis
Key facts
- Where
- Columbus, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 50 years old?
Source: NCT07163078, who can take part
Where in United States
- Nationwide Children's Hospital/ Ohio State UniversityColumbus, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Ohio State University
- Trial code
- NCT07163078
- Record updated
- 21 September 2026
- Original description
The goal of this study is to learn if one nutrition supplement formula works better than a different formula in adults with cystic fibrosis. The main question being addressed is: Will certain atypical versions of certain nutrients outperform typical versions of these nutrients? This will be determined by examining blood measures of nutrient levels and/or indications of nutrient function indicators pre- and post-intervention. Participants will take the supplements for 6 weeks with a blood draw before and after that time.Read full original descriptionShow less
A Medical Nutrition Supplement for Cystic Fibrosis
The goal of this study is to learn if one nutrition supplement formula works better than a different formula in adults with cystic fibrosis. The main question being addressed is: Will certain atypical versions of certain nutrients outperform typical versions of these nutrients? This will be determined by examining blood measures of nutrient levels and/or indications of nutrient function indicators pre- and post-intervention. Participants will take the supplements for 6 weeks with a blood draw before and after that time.
Inclusion: Diagnosed with cystic fibrosis; Diagnosed with exocrine pancreatic insufficiency; 18 years old or older; Currently on modulator; Normal liver enzyme labs.
Exclusion: If patients are currently taking Category A or Category B in the LiverTox categorization system; Patients that are on other medications that are sensitive CYP3A4 substrates - such as tacrolimus for example; History of liver abnormalities; Persistent elevation of liver enzymes >6 months (E2) (ALT >80 U/L); Non-English-speaking participants; Acute health crisis; Recent vitamin D supplementation of 30 mcg/day or higher, vitamin E supplements of 200 IU/day or higher, or copper at 2 mg/day or higher; Any other concern by investigator that the subject is inappropriate for inclusion; Patients who is on a reduced dose of a CFTR modulator; Patients on azole antifungals (voriconazole, itraconazole, posaconzole, >7 days of fluconazole, etc.); Patients who binge drink EtOH - for men more than 2 drinks/day, for women more than 1 drink/ day; Patients on sensitive CYP3A4 substrates including but not limited to tacrolimus, sirolimus, and cyclosporine.