Studies how salt intake affects gut inflammation in people with Crohn's disease
Observes how salt in the diet may affect gut inflammation in adults with Crohn's disease.
Plain-language title generated from the registry record
Registry title: Protease Regulation and Impact of Sodium as Mechanisms of Inflammation in IBD
Key facts
- Where
- Hamilton, CanadaSee the 2 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with Crohn's disease. It studies how eating salt affects gut health and inflammation.
- Age
- 18 to 70 years
- Sex
- All sexes can join.
- Earlier treatment
- Cannot have taken antibiotics, antibacterial agents or probiotics now or in the last 8 weeks.
Main reasons for not taking part
- Antibiotics, antibacterial agents or probiotics now or within the last 8 weeks
- Alcohol or drug abuse
- Pregnancy
- Another body-wide disease or lab abnormalities the investigators see as a risk or that could interfere with data collection
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Source: NCT07169123, who can take part
Where in Canada
- McMaster UniversityHamilton, CanadaContact: David Armstrong MD, MDTaking people
- McMaster University Medical CentreHamilton, CanadaContact: David Armstrong, MDNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- McMaster University
- Trial code
- NCT07169123
- Record updated
- 30 July 2026
- Original description
The study looks at how eating salt affects gut health in people with Crohn's disease. The aim of the study is to find out whether eating more salt increases the breakdown of proteins in the gut and if this makes inflammation and symptoms worse. By studying the link between salt, gut bacteria and inflammation, the study hopes to improve diet advice for people with Crohn's disease. This research may help find specific foods that affect the disease and lead to better, more personalized nutrition plans.Read full original descriptionShow less
Protease Regulation and Impact of Sodium as Mechanisms of Inflammation in IBD
The study looks at how eating salt affects gut health in people with Crohn's disease. The aim of the study is to find out whether eating more salt increases the breakdown of proteins in the gut and if this makes inflammation and symptoms worse. By studying the link between salt, gut bacteria and inflammation, the study hopes to improve diet advice for people with Crohn's disease. This research may help find specific foods that affect the disease and lead to better, more personalized nutrition plans.
Inclusion: 18 and 70 years of age; Crohn's disease diagnosis; Willing and able to sign written informed consent prior to study entry; Able to comply with the study procedures, in the opinion of the investigator.
Exclusion: Alcohol or drug abuse; Concurrent systemic disease and/or laboratory abnormalities considered by investigators to be a risk or that could interfere with data collection; Antibiotics, antibacterial agents, or probiotics, currently, or within the last 8 weeks; Pregnancy.