Tests a protein drink with HMB for muscle loss in Crohn's disease
Tests a protein supplement with HMB in adults with active Crohn's disease and muscle loss.
Plain-language title generated from the registry record
Registry title: High-protein Oral Nutrition With HMB for Active CD Patients With Sarcopenia
Key facts
- Where
- Guangzhou, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 50 years old?
Source: NCT07171593, who can take part
Where in China
- Sixth Hospital Affiliated to Sun Yat-sen UniversityGuangzhou, ChinaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Sixth Affiliated Hospital, Sun Yat-sen University
- Trial code
- NCT07171593
- Record updated
- 12 September 2025
- Original description
The efficacy of B-hydroxy-β-methybutyrate in sarcopeniaRead full original descriptionShow less
Efficacy of High-protein Oral Enteral Nutrition Supplement Supplemented With HMB in Active Crohn's Disease With Sarcopenia: a Prospective, Randomized, Controlled Study
The efficacy of B-hydroxy-β-methybutyrate in sarcopenia
Inclusion: Patients with active Crohn's disease (CD) who visited the Sixth Affiliated Hospital of Sun Yat-sen University between July 2023 and December 2024; Aged 18-50 years; Complicated with sarcopenia; Willing and able to tolerate oral exclusive enteral nutrition (EEN) therapy; Signed informed consent and able to comply with the study procedures; Colonic or ileocolonic type CD (SES-CD ≥6; if only terminal ileum is involved, SES-CD ≥4).
Exclusion: Underwent CD-related intestinal surgery or received biologic therapy within the past month, or received immunosuppressive/antibiotic therapy related to CD within 2 weeks prior to enrollment; Short bowel syndrome; High-output jejunal fistula; Complete mechanical intestinal obstruction, acute gastrointestinal bleeding, or severe intra-abdominal infection; Severe hepatic, renal, or cardiac diseases, or malignant tumors; History of allergy or contraindication to Ensure or HMB; Congenital disorders of sugar or amino acid metabolism; Severe stress or shock status; Persistent severe vomiting or intractable diarrhea.