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Tracking daily activity, sitting and sleep in pregnancy and babies' health

Observes pregnant people's sitting, activity and sleep, then their babies' growth and heart risk.

Plain-language title generated from the registry record
Registry title: Pregnancy 24/7 Offspring Study

Key facts

Where
Iowa City, Morgantown, and Pittsburgh, United StatesSee the 3 sites

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 0 and 47 years old?

Source: NCT07172880, who can take part

Where in United States

  • University of IowaIowa City, United StatesTaking people
  • West Virginia UniversityMorgantown, United StatesTaking people
  • University of PittsburghPittsburgh, United StatesNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Kara Whitaker
Trial code
NCT07172880
Record updated
2 November 2026
Original description
There is growing evidence that maternal health and behaviors in pregnancy, such as pre-pregnancy obesity, excessive gestational weight gain, poor diet, smoking, and adverse pregnancy outcomes, are linked to fetal programming for obesity and cardiovascular disease (CVD) risk in the offspring. Yet, there is a surprising lack of research on the role of prenatal sedentary behavior, physical activity, and sleep (conceptualized together as 24-hour behavior) on offspring obesity risk and CVD risk; this is an unfortunate research gap since there is strong physiological rationale that these behaviors in pregnancy could influence offspring health and are modifiable intervention targets in pregnancy. This multi-site observational cohort study will leverage state-of-the-art, 24-hour behavior assessment in each trimester of pregnancy, collected as part of the Pregnancy 24/7 cohort study and add additional assessments of offspring growth, adiposity, and CVD risk through 24 months to inform future primordial prevention interventions to decrease the risk of offspring obesity and CVD across the lifespan.Read full original descriptionShow less

Sedentary Behavior, Physical Activity, and 24-hour Behavior in Pregnancy and Offspring Health: the Pregnancy 24/7 Offspring Study

There is growing evidence that maternal health and behaviors in pregnancy, such as pre-pregnancy obesity, excessive gestational weight gain, poor diet, smoking, and adverse pregnancy outcomes, are linked to fetal programming for obesity and cardiovascular disease (CVD) risk in the offspring. Yet, there is a surprising lack of research on the role of prenatal sedentary behavior, physical activity, and sleep (conceptualized together as 24-hour behavior) on offspring obesity risk and CVD risk; this is an unfortunate research gap since there is strong physiological rationale that these behaviors in pregnancy could influence offspring health and are modifiable intervention targets in pregnancy. This multi-site observational cohort study will leverage state-of-the-art, 24-hour behavior assessment in each trimester of pregnancy, collected as part of the Pregnancy 24/7 cohort study and add additional assessments of offspring growth, adiposity, and CVD risk through 24 months to inform future primordial prevention interventions to decrease the risk of offspring obesity and CVD across the lifespan.

Maternal Inclusion Criteria:; Enrolled in Pregnancy 24/7 Study; Completed at least one 24-hr behavior assessment, with valid objective activity monitor data and questionnaires; Pregnancy resulted in singleton live birth; Offspring Exclusion Criteria:; -Child diagnosed with congenital or chromosomal abnormalities that may affect growth or CVD risk.

ClinicalTrials.gov NCT07172880