Screening urban adults at risk for hidden heart failure using cardiac MRI
Studies whether a mobile screening approach finds hidden heart failure in adults at risk.
Plain-language title generated from the registry record
Registry title: Determination of the Prevalence of Unrecognized Heart Failure Among Patients at Risk in Urban Areas Across Germany Using CMR
Key facts
- Where
- Berlin, GermanySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 69 years old?
Source: NCT07185100, who can take part
Where in Germany
- Deutsches Herzzentrum der CharitéBerlin, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- German Heart Institute
- Trial code
- NCT07185100
- Record updated
- 1 April 2026
- Original description
Heart failure (HF) in patients at risk is often overlooked, and when detected, there is a lack of early and effective preventive interventions. The WE-CARE-HF-CMR study, conducted in large cities/metropol areas in Germany ( > 1.000.000 inhabitants), aims to close this gap by evaluating the feasibility of a mobile, telemedicinemonitored HF-screening approach combining cardiac magnetic resonance imaging (CMR), quality of life assessment and laboratory tests as key elements in asymptomatic patients at risk. WE-CARE-HF-CMR will provide a proposal for a comprehensive, contemporary screening approach for patients at risk to develop HF tailored to the needs of the target population. This will provide important new information on the prevalence of asymptomatic HF in at-risk patients in urban versus rural areas.Read full original descriptionShow less
A Prospective, Cross-sectional, Nationwide Community-based Observational Study to Determine the Prevalence of Unrecognized Heart Failure Among Patients at Risk in Urban Areas Across Germany Using CMR
Heart failure (HF) in patients at risk is often overlooked, and when detected, there is a lack of early and effective preventive interventions. The WE-CARE-HF-CMR study, conducted in large cities/metropol areas in Germany ( > 1.000.000 inhabitants), aims to close this gap by evaluating the feasibility of a mobile, telemedicinemonitored HF-screening approach combining cardiac magnetic resonance imaging (CMR), quality of life assessment and laboratory tests as key elements in asymptomatic patients at risk. WE-CARE-HF-CMR will provide a proposal for a comprehensive, contemporary screening approach for patients at risk to develop HF tailored to the needs of the target population. This will provide important new information on the prevalence of asymptomatic HF in at-risk patients in urban versus rural areas.
The results of the study will be compared with the results from the "HERZCheck'' trial, which provides data from approximately 4,500 participants in rural areas in Germany and has already been completed (NCT05122793).
Inclusion: Asymptomatic subjects with:; chronic diabetes mellitus (known/diagnosed and/or antidiabetic medication and/or elevated HbA1C) and/or; renal impairment (known/diagnosed CKD and/or in laboratory CKD III° or higher) and/or; Hypertension (known/diagnosed and/or antihypertensive medication/treatment) and/or; Hypercholesterolaemia (known/diagnosed and/or antilipid medication/treatment) and/or; Obesity (known/diagnosed and/or BMI > 30 (kg/m²)) and/or; Smoker (known/diagnosed and/or current/previous and/or medication/treatment); Age 40-69 years; female or male or diverse sex; Ability to provide informed consent; Provision of Informed Consent.
Exclusion: Haemodynamically unstable participants (heart rate < 45/min, systolic blood pressure < 90 mmHg); Acute mental disorders requiring therapy; Diagnosed heart failure or previously detected reduced ejection fraction; Any MRI exclusion criteria not listed here, as determined by the MRI laboratory performing the procedure; Inability to provide written informed consent; General MRI exclusion criteria (pacemaker, defibrillator, intracranial aneurysm clips, metallic foreign bodies in the eyes); Claustrophobia; Sensorineural hearing loss of 30 dB or more and tinnitus; In the presence of pregnancy.