Heart failure trials in Germany

In Germany 111 Also abroad 1261

111 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Routine Microaxial Heart Pump Support and Protocolized Pulmonary Artery Catheter Monitoring Versus Standard Care in Heart Attack-Related Cardiogenic Shock
Where
Leipzig
Age
18 years to 80 years
People
780
Run by
Leipzig Heart Science gGmbH
See details and how to joinNCT07762560
No phaseTaking people
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Where
Berlin, Hanover, Leipzig
Age
18 years and over
People
850 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT06526195
No phaseTaking people
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
Where
Aachen, Bad Oeynhausen, Bielefeld, Bremen, Cologne, Dresden, Düsseldorf, Essen, Hamburg, Hanover, Heidelberg, Homburg, Jena, München, Münster, Tübingen, Ulm, Villingen-Schwenningen
People
20,000 worldwide
Run by
Medtronic
See details and how to joinNCT00271180
Phase 3Taking people
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Where
Bad Nauheim, Bonn, Erfurt, Frankfurt Am Main, Goettingen, Hamburg, Heidelberg, Homburg, Jena, Langen (Hesse), Mainz, Markkleeberg, Munich, Wuerzburg
Age
18 years to 85 years
People
1,800 worldwide
Run by
Cytokinetics
See details and how to joinNCT06736574 · EU 2024-519219-32-00
Phase 3Taking people
Effects of Continued Administration of Empagliflozin in Patients With Heart Failure on Active SGLT2 Inhibitor Treatment Admitted for Acute Decompensated Heart Failure
Where
Bad Nauheim, Berlin, Bonn, Dresden, Goettingen, Greifswald, Halle (Saale), Jena, Leipzig, Magdeburg, Mainz, Munich, Rostock
Age
18 years and over
People
536
Run by
Christian Schulze
See details and how to joinNCT07038356 · EU 2024-517977-26-00
No phaseTaking people
Mitral Valve Edge-to-Edge Repair in Patients With Exercise-Induced Severe Mitral Regurgitation
Where
Düsseldorf, Jena
Age
18 years and over
People
246
Run by
Jena University Hospital
See details and how to joinNCT07709208
No phaseTaking people
ELEVATE-HFpEF Clinical Study
Where
Lübeck
Age
40 years and over
People
700 worldwide
Run by
Medtronic Cardiac Rhythm and Heart Failure
See details and how to joinNCT06678841
No phaseTaking people
Achieving Optimal Medical Therapy Through Percutaneous Treatment of Secondary Mitral Regurgitation to Improve Outcome in Patients With HFrEF
Where
Mainz
Age
18 years and over
People
520
Run by
University Medical Center Mainz
See details and how to joinNCT07758023
Phase 2/3Taking people
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Where
Berlin, Erlangen, Freiburg im Breisgau, Hanover, Heidelberg
Age
29 days to 17 years
People
342 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT05714085 · EU 2022-501238-52-00
Phase 3Taking people
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Where
Bad Berka, Bad Neustadt an der Saale, Bad Segeberg, Berlin, Bonn, Detmold, Dortmund, Dresden, Düsseldorf, Frankfurt am Main, Fulda, Göttingen, Hamburg, Haßloch, Heidelberg, Homburg, Jena, Kaiserslautern, Leipzig, Leverkusen, Mainz, Mannheim, Minden, München, Offenbach, Papenburg, Regensburg, Schwäbisch Hall, Siegen, Ulm, Wermsdorf
Age
18 years to 99 years
People
5,056 worldwide
Run by
Amgen
See details and how to joinNCT07037459
Phase 3Taking people
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Where
Aachen, Bad Friedrichshall, Berlin, Bonn, Dresden, Erfurt, Frankfurt am Main, Frankfurt Am Main, Hamburg, Hanover, Jena, Kamp-Lintfort, Kiel, Langen (Hesse), Leipzig, Lueneburg, Neuwied, Nürnberg, Papenburg, Regensburg, Stuhr, Wallerfing, Wermsdorf, Wiesbaden
Age
18 years and over
People
6,712 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT06424288 · EU 2023-509706-30-00
Phase 3Taking people
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Where
Bad Friedrichshall, Bamberg, Berlin, Bonn, Coburg, Dresden, Erfurt, Hamburg, Hanover, Kaiserslautern, Kiel, Langen (Hesse), Leipzig, Ludwigshafen Am Rhein, Lueneburg, Mannheim, Neuwied, Papenburg, Regensburg, Wallerfing, Wermsdorf, Wiesbaden, Worms
Age
18 years and over
People
4,200 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT06935370 · EU 2024-519525-38-00
Phase 3Taking people
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity (MARITIME-HF)
Where
Bad Berka, Bad Neustadt A.D.Saale, Bad Segeberg, Berlin, Bonn, Detmold, Dortmund, Dresden, Duesseldorf, Frankfurt am Main, Frankfurt Am Main, Fulda, Goettingen, Hamburg, Hassloch, Heidelberg, Homburg, Jena, Kaiserslautern, Leipzig, Leverkusen, Mainz, Mannheim, Minden, Munich, Offenbach Am Main, Papenburg, Regensburg, Schwäbisch Hall, Siegen, Ulm, Wermsdorf
Age
18 years and over
People
2,787 worldwide
Run by
Amgen Inc.
See details and how to join2024-516654-22-00 · EU 2024-516654-22-00
Phase 3Taking people
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
Where
Cologne, Giessen, Tuebingen
Age
Up to 18 years
People
117 worldwide
Run by
Bayer
See details and how to joinNCT07192952 · EU 2024-519830-22-00
No phaseTaking people
BIO|STREAM.CSP Study
Where
Augsburg, Bad Krozingen, Bad Nauheim, Bad Oeynhausen, Cologne, Osnabrück
Age
18 years and over
People
1,000 worldwide
Run by
Biotronik SE & Co. KG
See details and how to joinNCT07393009
No phaseTaking people
Reliability of Multiple-Repetition-Maximum Tests in Patients With Cardiovascular Disease or Risk Factors
Where
München
Age
50 years and over
People
50
Run by
Technical University of Munich
See details and how to joinNCT06796582
Phase 3Taking people
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
Where
Aachen, Amberg, Bad Oeynhausen, Bamberg, Bechhofen, Berlin, Bochum, Brandenburg An Der Havel, Bremen, Deggingen, Dresden, Elsterwerda, Essen, Frankfurt am Main, Freiburg im Breisgau, Friedrichsthal, Fulda, Gelnhausen, Goerlitz, Hamburg, Hassloch, Heidelberg, Homburg, Kaiserslautern, Kassel, Koeln, Langen (Hesse), Leipzig, Ludwigshafen Am Rhein, Mannheim, Markkleeberg, Neuruppin, Nittendorf, Obertshausen, Oldenburg in Holstein, Osnabrück, Papenburg, Pirna, Ratingen, Reinfeld, Wallerfing, Weinheim
Age
40 years and over
People
11,300 worldwide
Run by
AstraZeneca
See details and how to joinNCT06677060 · EU 2024-514506-32-00
Phase 3Taking people
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Where
Bad Oeynhausen, Berlin, Cologne, Dresden, Frankfurt am Main, Freiburg im Breisgau, Jena, Kiel, München, Munich, Münster, Würzburg
Age
18 years and over
People
1,280 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07207811
No phaseTaking people
CytOSorb TreatMent Of Critically Ill PatientS Registry
Where
Aachen, Bad Oeynhausen, Bochum, Essen, Göttingen, Herford, Jena, Kassel, Marburg, Mönchengladbach, Munchen, München, Oldenburg, Wiesbaden
People
3,000 worldwide
Run by
CytoSorbents, Inc
See details and how to joinNCT05146336
Phase 1Taking people
A research study looking into how a single dose of the medicine NNC0537-1482 moves through the body of participants with normal or reduced kidney function
Where
Berlin
Age
18 years and over
People
54
Run by
Novo Nordisk A/S
See details and how to join2026-525271-57-00 · EU 2026-525271-57-00
No phaseTaking people
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)
Where
Düsseldorf, Leipzig
Age
18 years and over
People
754 worldwide
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT05427370
Phase 3Taking people
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
Where
Cologne, Giessen, Tuebingen
Age
6 months to 17 years
People
111 worldwide
Run by
Bayer
See details and how to joinNCT07188805 · EU 2024-519829-38-00
Phase 2Taking people
Dose-finding Study of YMI024 to Assess Efficacy, Safety, and Tolerability in Adults With Stable Coronary Artery Disease and Elevated hsCRP
Where
Berlin, Essen, Freiburg im Breisgau, Gladbeck, Kaiserslautern, Konstanz, Leipzig, Loehne, Ludwigshafen, Mannheim, Pirna, Stuttgart, Ulm
Age
18 years to 80 years
People
180 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07830719 · EU 2026-525974-21-00
Phase 3Taking people
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
Where
Bad Nauheim, Bechhofen, Berlin, Bernau bei Berlin, Chemnitz, Coburg, Dresden, Elsterwerda, Frankfurt, Freiburg im Breisgau, Goslar, Göttingen, Hagen, Hamburg, Heidelberg, Kaiserslautern, Langen, Leipzig, Leverkusen, Mainz, Mönchengladbach, Münster, Paderborn, Papenburg, Regensburg, Rostock, Völklingen, Wermsdorf, Witten
Age
18 years to 130 years
People
3,850 worldwide
Run by
AstraZeneca
See details and how to joinNCT06307652 · EU 2023-508162-15-00
No phaseTaking people
Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)
Where
Giessen, Hanover, Heidelberg
Age
22 years and over
People
400 worldwide
Run by
Reprieve Cardiovascular, Inc
See details and how to joinNCT06898515