Compares two exercise and eating programs for type 2 diabetes risk in young people

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for teenagers and young adults with overweight or obesity. It compares a 4-week high-intensity interval training programme with time-restricted eating.

Age

14 to 30 years. Ages 14-17 and 18-30 have different weight rules.

Sex

All sexes can join.

Disease stage

Ages 14-17: BMI percentile of 85 or higher for their sex and race. Ages 18-30: BMI of 25 kg/m2 or higher.

Earlier treatment

People who have taken heart, lung, thyroid, cholesterol-lowering, blood sugar-lowering, blood pressure, hormone, psychiatric, nerve or anabolic steroid medicines cannot join.

Main reasons for not taking part

• Chronic conditions such as heart disease, diabetes, thyroid disease, hypertension, cancer or HIV
• Taking heart, lung, thyroid, diabetes, blood pressure or hormone medicines
• Taking psychiatric or neurological medicines
• Taking anabolic steroids
• Having a pacemaker

The registry criteria, word for word

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

• Are you between 14 and 30 years old?YesNo

What the trial wants to find out

The primary aim of this randomized controlled trial is to examine the effects of a 4-week high-intensity interval training (HIIT) and time-restricted eating (TRE) intervention on cardiometabolic biomarkers in adolescents and young adults.

The 3 groups in the trial

• High-intensity interval trainingTreatment being tested

  HIIT: The 4-week HIIT intervention will use a stationary bicycle performed 3 times/week (a total of 12 sessions over the 4-week), performing at the CRL. All participants will perform a 20-minute HIIT protocol (20 repetitions of 10-seconds work time followed by 50-seconds resting/active recovery for the first two weeks, and 10 repetitions of 20-seconds work time followed by 100-seonds resting/active recovery for the rest of two weeks; targeted 90% HRmax) after 5-minute warm-up (10% HRmax). The supervisor (PI: Joon Young Kim and/or Graduate researcher: Wonhee Cho) will provide encouragement and supervision for exercise adherence. Heart rate (Polar, Polar Electro Oy, Kempele, Finland) and rating of perceived exertion (RPE; detail described in the questionnaire section) will be recorded.

• Time-restricted eatingTreatment being tested

  Participants randomized into the TRE group will be instructed to consume all their calories within a 10-hour period. We will instruct participants that they can choose their time-window (early TRE \[7am - 5pm\] or late TRE \[1pm - 11pm\]), but it must remain constant for the duration of the study. Further, we will give no restrictions on the type of foods and/or the quantities individuals can consume. We will ask individuals to maintain their diet for the duration of the study. Participants will be given clear instructions on their diet and how to use the "MyFitnessPal" application. Participants will have their total daily energy requirement calculated using the following formula (Basal metabolic rate \[BMR\] x activity level) and will be told to eat that amount within their allotted time window. BMR will be calculated when participants have their body composition taken by the InBody. Participants will be told to start their 4-week diet the following day after visit.

• Control GroupNo study treatment, for comparison

  Participants randomized into the control group will be told to maintain their daily lifestyle and dietary habits for the duration of the four weeks.