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Tests deep magnetic brain stimulation for teens hospitalized with major depressive disorder

Tests deep magnetic brain stimulation as added treatment in hospitalized teens with depression.

Plain-language title generated from the registry record
Registry title: Improving Outcomes in Adolescent Inpatient Depression With Deep Transcranial Magnetic Stimulation

Key facts

Where
Cincinnati, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 14 and 18 years old?

Source: NCT07217444, who can take part

Where in United States

  • Cincinnati Childrens Hospital Medical CenterCincinnati, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Children's Hospital Medical Center, Cincinnati
Trial code
NCT07217444
Record updated
11 February 2026
Original description
Evaluate the feasibility, safety, and preliminary efficacy of deep Transcranial Magnetic Stimulation (dTMS) as an adjunctive treatment for adolescents hospitalized with major depressive disorder (MDD).Read full original descriptionShow less

Improving Outcomes in Adolescent Inpatient Depression With Deep Transcranial Magnetic Stimulation

Evaluate the feasibility, safety, and preliminary efficacy of deep Transcranial Magnetic Stimulation (dTMS) as an adjunctive treatment for adolescents hospitalized with major depressive disorder (MDD).

Inclusion: Fluent in English and able to volunteer in the informed consent process and provide spontaneous narrative description of key elements, risks, and benefits of the study; Aged 14 years to 18 years, inclusive; Diagnosis of MDD based on psychologist diagnosis and DSM-5-checklist based interview; Symptoms of moderate to severe depression according to Hamilton Depression Rating Scale Score > 20; Participants are not required to discontinue current interventions.

Exclusion: Participation in an investigational drug trial within the past three months; Contraindications to Transcranial Magnetic Stimulation including, but not limited to, a history of epilepsy, the presence of metallic foreign bodies, or implanted medical devices (e.g. ventriculoperitoneal shunt, pacemaker, medical pump); Actively psychotic (i.e. disorganized, delusional, paranoid, or having hallucinations); Actively suicidal (have a suicidal plan and intent and is on 1:1 close observation); For female subjects of childbearing potential, a positive urine pregnancy test.

ClinicalTrials.gov NCT07217444