Sleep Disruption and Irregular Heartbeats in Adults With Sleep Apnea
Tests whether one night of disrupted sleep triggers irregular heartbeats in adults with sleep apnea.
Plain-language title generated from the registry record
Registry title: Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation
Key facts
- Where
- San Francisco, United StatesSee the site
Where in United States
- UCSF Medical Center at ParnassusSan Francisco, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of California, San Francisco
- Trial code
- NCT07220525
- Record updated
- 2 October 2026
- Original description
Whereas the available evidence mostly supports chronic sleep disruption as a risk factor for incident AF, less is known about the near-term risk of a discrete atrial fibrillation (AF) episode following a night of disrupted or poor-quality sleep. This prospective, randomized, case-crossover study aims to examine the acute effects of sleep disruption on clinically relevant cardiac ectopy pertinent to AF.Read full original descriptionShow less
Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation
Whereas the available evidence mostly supports chronic sleep disruption as a risk factor for incident AF, less is known about the near-term risk of a discrete atrial fibrillation (AF) episode following a night of disrupted or poor-quality sleep. This prospective, randomized, case-crossover study aims to examine the acute effects of sleep disruption on clinically relevant cardiac ectopy pertinent to AF.
Inclusion: Are age 21 years or older; Have a HGNS device implanted for obstructive sleep apnea and followed up at UCSF Health; Are willing to abstain from using the upper airway stimulation device for no more than two consecutive days as instructed over the 14-day trial period; Able and willing to provide written informed consent.
Exclusion: Are currently taking class 1 or 3 anti-arrhythmic medications; Have a history of permanent AF or expected to have continuous AF throughout the study period; Have congenital heart disease; Currently pregnant or trying to get pregnant; Ventricular pacing >40%; Are unable to read or sign to provide informed consent.