Studying Infections and Inflammation in People With ME/CFS
Observes people with ME/CFS and healthy volunteers over time to study biological causes.
Plain-language title generated from the registry record
Registry title: Chronic Infections and Inflammation in ME/CFS: An Observational Study
Key facts
- Where
- San Francisco, United StatesSee the site
Where in United States
- Zuckerberg San Francisco General HospitalSan Francisco, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of California, San Francisco
- Trial code
- NCT07227441
- Record updated
- 6 March 2026
- Original description
CHIIME is a study of people who have myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). People who do not have this condition will also be enrolled. Volunteers will be observed and sampled over time to identify the long-terms biological drivers and impact of their condition. The overall goal is to understand the biological and physiological mechanisms that are driving this condition.Read full original descriptionShow less
Chronic Infections and Inflammation in ME/CFS: An Observational Study
CHIIME is a study of people who have myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). People who do not have this condition will also be enrolled. Volunteers will be observed and sampled over time to identify the long-terms biological drivers and impact of their condition. The overall goal is to understand the biological and physiological mechanisms that are driving this condition.
Inclusion: Willing and able to provide written informed consent; At least 18 years of age; Either: (1) a reported diagnosis of ME/CFS or (2) no history of ME/CFS or other infection-associated chronic conditions (healthy control).
Exclusion: Active drug or alcohol use or dependence that, in the opinion of the PI, would interfere with adherence to study requirements or to give informed consent; Known HIV, hepatitis B, or hepatitis C infection; Diagnosis of an infection-associated chronic condition other than ME/CFS or Long COVID (e.g. chronic Lyme disease, post-Ebola syndrome, etc.); Serious medical or psychiatric illness that, in the opinion of the site investigator, would interfere with the ability to adhere to study requirements or to give informed consent; Self reported or documented chronic anemia with hemoglobin <9 g/dL.