Pharmacist-led nudges to encourage single-pill blood pressure medicines
Tests pharmacist-led nudges for providers and patients to increase single-pill blood pressure medicine use.
Plain-language title generated from the registry record
Registry title: Fixed-Dose Combinations Pragmatic Randomized Implementation Trial for Blood Pressure Control
Key facts
- Where
- Milwaukee, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07228065, who can take part
Where in United States
- Advocate HealthMilwaukee, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Brigham and Women's Hospital
- Trial code
- NCT07228065
- Record updated
- 11 August 2026
- Original description
The proposed study is an effectiveness-implementation hybrid type II trial designed to evaluate the impact of provider- and patient-directed interventions on FDC use. The trial will test the effectiveness of theory-driven nudges tailored to address provider and patient barriers. All interventions will be pharmacist-driven, with pharmacists delivering information via nudges to providers and via nudges or more intensive interventions (i.e., CPA) to patients. Data to evaluate outcomes will be extracted from electronic health records.Read full original descriptionShow less
Pharmacy-led Intervention to Increase the Adoption of Fixed-dose Single Pill Blood Pressure Lowering Medications: Hybrid Effectiveness-Implementation Trial
The proposed study is an effectiveness-implementation hybrid type II trial designed to evaluate the impact of provider- and patient-directed interventions on FDC use. The trial will test the effectiveness of theory-driven nudges tailored to address provider and patient barriers. All interventions will be pharmacist-driven, with pharmacists delivering information via nudges to providers and via nudges or more intensive interventions (i.e., CPA) to patients. Data to evaluate outcomes will be extracted from electronic health records.
Inclusion: patients with documented hypertension diagnosis; had an elevated ambulatory blood pressure reading during the qualifying visit (systolic >140 mmHg or diastolic >90 mmHg; have an upcoming scheduled visit; have an active prescription for 1 blood pressure lowering medication with a fixed-dose combination (FDC) alternative.
Exclusion: have received a prescription for a FDC in the preceding two years; have a documented allergy to any FDC components; have a diagnosis of heart failure or renal failure, given that antihypertensive management in these populations typically requires disease-specific regimens and more frequent treatment adjustments; reside in a nursing home; are pregnant; preferred language is not English or Spanish, defined as documentation in the EHR indicating a primary language other than English or Spanish, or a documented request for an interpreter in a language other than Spanish.