Potato-rich diet and cardiometabolic health in older adults at risk of type 2 diabetes
Compares a potato-rich diet with a Western-style diet in older adults at risk of diabetes.
Plain-language title generated from the registry record
Registry title: Potatoes, Type 2 Diabetes, and Cardiometabolic Health
Key facts
- Where
- Blacksburg, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 50 and 70 years old?
Source: NCT07229482, who can take part
Where in United States
- Virginia Polytechnic Institute and State UniversityBlacksburg, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Virginia Polytechnic Institute and State University
- Trial code
- NCT07229482
- Record updated
- 3 September 2026
- Original description
Type 2 diabetes (T2D) is a major chronic health condition which increases risk of coronary artery disease, frailty, cognitive decline, and mortality. Additionally, hypertension is a major comorbidity for individuals with T2D, further increasing the risk of adverse cardiovascular outcomes. The prevalence of both conditions increases with advancing age. There is an urgent need to identify new approaches to prevent the development of T2D and improve cardiometabolic health in older adults 50-70 years of age.Read full original descriptionShow less
Cardiometabolic Effects of a Potato-rich Diet in Older Adults at Increased Risk of Developing Type 2 Diabetes: A Randomized Controlled Feeding Study
Type 2 diabetes (T2D) is a major chronic health condition which increases risk of coronary artery disease, frailty, cognitive decline, and mortality. Additionally, hypertension is a major comorbidity for individuals with T2D, further increasing the risk of adverse cardiovascular outcomes. The prevalence of both conditions increases with advancing age. There is an urgent need to identify new approaches to prevent the development of T2D and improve cardiometabolic health in older adults 50-70 years of age.
Whole white potatoes are an unprocessed food rich in essential nutrients often under-consumed by Americans, including potassium, fiber, magnesium, vitamins C and B6, and phytochemicals. Each of these nutrients individually are associated with cardiometabolic health benefits. Potatoes account for a significant amount of the intake of these nutrients in the US diet and are well-positioned to be a foundational element of a healthy dietary pattern. However, there are few interventional studies evaluating the effect of potatoes on cardiometabolic health, and the evidence from observational studies is mixed, leaving a significant gap in knowledge regarding the potential for potatoes to be included in healthy dietary patterns.
The results of our proposed study will provide foundational data that inform future dietary guidelines regarding the inclusion of white potatoes as part of a healthy US dietary pattern.
Inclusion: Age 50-70 years; Weight stable for previous 3 months (±5% body weight); Sedentary to recreationally active; ADA-Risk Screener questionnaire score of at least 5; No plans to gain or lose weight or change physical activity level; Willing to pick up food daily and consume foods provided for a 14-week period; Verbal and written informed consent; Estrogen or testosterone use, lipid-lowering or blood pressure medication and thyroid replacement medication is acceptable, if on stable dose for >6 months.
Exclusion: Antibiotic, prebiotic or probiotic use in prior 3 months; Estrogen or testosterone usage, lipid-lowering medication, blood pressure medication usage <6 months; Diabetes or diabetes medication; Diagnosed inflammatory bowel disease; Past or current heart diseases, stroke, respiratory disease, endocrine or metabolic disease, or hematological-oncological disease; Food allergies or aversions to diet foods provided; Weight loss medication or medication influencing glucose metabolism; TCHOL >6.2 mmol/L; TG >4.5 mmol/L; Body mass index >40 m2/kg; Blood pressure (BP) > 159/99 mmHg; Vegetarian or vegan; Pregnant or plans to become pregnant.