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Uses home blood pressure readings to adjust medicines for uncontrolled high blood pressure

Tests home blood pressure readings to guide medicine changes in adults with high blood pressure.

Key facts

Who runs it
Anita Misra-Hebert
Where
Cleveland, United StatesSee the site
Trial code
Registry title
Implementation of Intensive Hypertension Management Approaches: Cleveland Clinic
Status
Recruiting
People taking part
1,520 people, planned
Started
6 Jan 2026
Expected to end
Jul 2029
Type of study
Observational
Treatments tested
  • IN-HOME BP
Record updated
9 January 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with high blood pressure that is not well controlled. It tests adjusting blood pressure medicine using readings taken at home.

Age
18 to 85 years
Sex
All sexes can join.
Disease stage
Diagnosed hypertension (high blood pressure) with a reading above 150/95.

Main reasons for not taking part

  • Pregnancy
  • Stage 5 chronic kidney disease
  • End Stage Renal Disease
  • Enrolled in hospice care

The registry criteria, word for word

Show all 3 criteriaShow less

Who can take part

  • Hypertension diagnosis, aged 18-85 years old
  • Uncontrolled blood pressure, defined as a blood pressure reading of > 150/95

Who cannot take part

  • pregnant, stage 5 chronic kidney disease, End Stage Renal Disease, enrolled in hospice care

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 85 years old?

Where in United States

  • Cleveland ClinicCleveland, United StatesContact: Anita Misra-Hebert, MD, MPH, FACPTaking people

About the trial

What the trial wants to find out

The primary objective of the Implementation of Effective Hypertension Management Approaches: Cleveland Clinic program is to improve blood pressure control for patients diagnosed with hypertension (HTN) and uncontrolled blood pressure, specifically defined as a blood pressure greater than 150/95, across all Cleveland Clinic Northeast Ohio primary care practices. The project will scale up the availability of resources for treating hypertension in 56 primary care practices within the Cleveland Clinic Health System in Northern Ohio, reaching up to approximately 3800 patients. This project will utilize evidence from a randomized controlled trial by Margolis et al.(1) to build upon Cleveland Clinic's existing team-based primary care provider (PCP) collaboration with pharmacists and advanced practice providers (APP) and will use a mechanism that allows titrating blood pressure medications based on patient-recorded home blood pressure readings.

The group in the trial

  • IN-HOME BP: titrating BP medications based on patient-recorded home blood pressure readings

    This project will utilize evidence from a randomized controlled trial by Margolis et al.(1) to build upon Cleveland Clinic's existing team-based primary care provider (PCP) collaboration with pharmacists and advanced practice providers (APP) and will use a mechanism that allows titrating blood pressure medications based on patient-recorded home blood pressure readings.

    Treatment: IN-HOME BP

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Implementation of Intensive Hypertension Management Approaches: Cleveland Clinic
Plain-language title
Uses home blood pressure readings to adjust medicines for uncontrolled high blood pressureGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Fit questions
Built from NCT07232017, who can take part
Record updated
9 January 2026