Daily pistachios for adults taking GLP-1 medicines such as semaglutide or tirzepatide
Tests eating pistachios daily in adults on GLP-1 weight-loss medicines.
Key facts
- Who runs it
- Ian J. Neeland, MD
- Where
- Clevland, United StatesSee the site
- Trial code
- Registry title
- Pistachio Intake and Nutrition-Related Outcomes in Individuals on GLP-1 Therapy
- Status
- Recruiting
- People taking part
- 108 people, planned
- Started
- 29 Jan 2026
- Expected to end
- Dec 2027
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Pistachios
- Dual-energy X-ray absorptiometry (DEXA) scans
- Record updated
- 20 February 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with overweight or obesity who have been taking semaglutide or tirzepatide for at least three months and are still taking it.
- Age
- 18 to 80 years
- Sex
- All sexes can join.
- Disease stage
- BMI of 30 kg/m2 or higher, or BMI of 27 kg/m2 or higher with at least one weight-related health condition.
- Earlier treatment
- Must have used semaglutide or tirzepatide continuously for three months for a clinical indication, and still be on it when joining.
Main reasons for not taking part
- Not using a GLP-1 RA, or cannot use one
- Known allergy to nuts
- Pregnant or breastfeeding
- Incarcerated
The registry criteria, word for word
Show all 5 criteriaShow less
Who can take part
- Individuals with a BMI ≥30 kg/m2 or with a BMI ≥27 kg/m2 with at least one weight-related comorbidity who have been continuously using semaglutide or tirzepatide for three months for a clinical indication and remain on the therapy at the time of enrollment
Who cannot take part
- Known allergy to nuts
- No use or contraindication to use of a GLP-1 RA
- Pregnant or breastfeeding
- Incarcerated
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Where in United States
- University Hospitals Cleveland Medical CenterClevland, United StatesContact: Ian Neeland, MDTaking people
About the trial
What the trial wants to find out
In this study will look at how eating pistachios every day might affect participants weight, how healthy their diet is, and how they feel when eating. Investigators want to see if adding pistachios to meals for 12 weeks helps participants feel fuller, have more energy, and improve body composition. The study will include adults who have been taking GLP-1 medicines like semaglutide or tirzepatide for at least three months. Investigators also want to see if eating pistachios improves overall diet quality and health markers like tiredness and certain levels in blood.
The 2 groups in the trial
- Pistachio GroupTreatment being tested
Participants in this group will eat 2 ounces, or 53 grams of dry-roasted, unsalted pistachios each day along with their regular diet.
Treatment: Pistachios and Dual-energy X-ray absorptiometry (DEXA) scans
- No Pistachio GroupExisting treatment, for comparison
Participants in this group will continue eating regular diet without pistachios.
Treatment: Dual-energy X-ray absorptiometry (DEXA) scans
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Dietary Pistachio Intake and Nutrition-Related Outcomes in Individuals Using GLP-1 Receptor Agonists: A Randomized Controlled Trial
- Plain-language title
- Daily pistachios for adults taking GLP-1 medicines such as semaglutide or tirzepatideGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT07244445, who can take part
- Record updated
- 20 February 2026