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Eating peanuts daily in adults using GLP-1 weight-loss medicines

Tests daily peanuts for 12 weeks in adults taking GLP-1 medicines.

Key facts

Who runs it
Ian J. Neeland, MD
Where
Clevland, United StatesSee the site
Trial code
Registry title
Dietary Peanuts and Nutrition-Related Outcomes
Status
Recruiting
People taking part
64 people, planned
Started
20 Apr 2026
Expected to end
Dec 2027
Type of study
Interventional, 2 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • Peanuts
  • Dual-energy X-ray absorptiometry (DEXA) scans
Record updated
23 April 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults who use semaglutide or tirzepatide and have a high body weight. People will add peanuts to their meals for 12 weeks.

Age
18 to 80 years
Sex
All sexes can join.
Disease stage
BMI of 30 kg/m2 or more, or BMI of 27 kg/m2 or more with at least one health problem related to weight.
Earlier treatment
Must be using semaglutide or tirzepatide for a clinical indication or for at least 6 months.

Main reasons for not taking part

  • Not using a GLP-1 RA, or cannot use one
  • Known allergy to nuts
  • Pregnant or breastfeeding
  • Incarcerated

The registry criteria, word for word

Show all 5 criteriaShow less

Who can take part

  • Individuals with a BMI ≥30 kg/m2 or with a BMI ≥27 kg/m2 with at least one weight-related comorbidity who have been using semaglutide or tirzepatide for a clinical indication or at least 6 months

Who cannot take part

  • Known allergy to nuts
  • No use or contraindication to use of a GLP-1 RA
  • Pregnant or breastfeeding
  • Incarcerated

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 80 years old?

Where in United States

  • University Hospitals Cleveland Medical CenterClevland, United StatesContact: Ian Neeland, MDTaking people

About the trial

What the trial wants to find out

This study will look at how eating peanuts every day might affect participants weight, how healthy their diet is, and how they feel when eating. Investigators want to see if adding peanuts to meals for 12 weeks helps participants feel fuller, have more energy, and improve body composition. The study will include adults who have been taking GLP-1 medicines like semaglutide or tirzepatide for at least three months. Investigators also want to see if eating peanuts improves overall diet quality and health markers like tiredness and certain levels in blood.

The 2 groups in the trial

  • Peanut GroupTreatment being tested

    Participants in this group will eat 2 ounces, or 53 grams of dry-roasted, lightly salted (low sodium) each day along with their regular diet.

    Treatment: Peanuts and Dual-energy X-ray absorptiometry (DEXA) scans

  • No Peanut GroupExisting treatment, for comparison

    Participants in this group will continue eating regular diet without peanuts.

    Treatment: Dual-energy X-ray absorptiometry (DEXA) scans

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Dietary Peanut Intake and Nutrition-Related Outcomes in Individuals Using GLP-1 Receptor Agonists: A Randomized Controlled Trial
Plain-language title
Eating peanuts daily in adults using GLP-1 weight-loss medicinesGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Fit questions
Built from NCT07244458, who can take part
Record updated
23 April 2026