Tirzepatide compared with usual care in adults with obesity but not diabetes
Tests tirzepatide against usual care for weight loss in adults with obesity.
Plain-language title generated from the registry record
Registry title: A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK)
Key facts
- Where
- Altrincham, Ashton-under-Lyne, Bolton, Bury, Cheshire, Great Lever, Hyde SK14, Manchester, Oldham, Rochdale, Sale, Salford, Stockport, Swinton, and Wigen, United KingdomSee the 30 sites
- Phase
- Phase 4
Where in United Kingdom
- P91604 St John's Medical CentreAltrincham, United KingdomNot yet recruiting
- P89008 Ashton Medical GroupAshton-under-Lyne, United KingdomTaking people
- Y02319 SSP Bolton General PracticeBolton, United KingdomNot yet recruiting
- P83012 Tower Family HealthcareBury, United KingdomNot yet recruiting
- P88007 Cheadle Hulme Medical Group (was Cheadle Hulme Health Centre) (Bridge House)Cheshire, United KingdomNot yet recruiting
- P91014 Washway Road Medical CentreCheshire, United KingdomNot yet recruiting
- Y02790 SSP Bolton Medical CentreGreat Lever, United KingdomNot yet recruiting
- P89002 The Brooke SurgeryHyde SK14, United KingdomTaking people
- P83025 St Gabriels Medical CentreManchester, United KingdomNot yet recruiting
- P84012 Northenden Group PracticeManchester, United KingdomNot yet recruiting
- P84017 Ladybarn Group PracticeManchester, United KingdomNot yet recruiting
- P84034 Barlow Medical CentreManchester, United KingdomNot yet recruiting
- P84035 Bodey Medical CentreManchester, United KingdomTaking people
- P84068 Chorlton Family PracticeManchester, United KingdomNot yet recruiting
- P84630 The Arch Medical PracticeManchester, United KingdomTaking people
- P84678 Didsbury Medical CentreManchester, United KingdomNot yet recruiting
- P86004 Peterloo Medical CentreManchester, United KingdomTaking people
- P87019 Silverdale Medical PracticeManchester, United KingdomTaking people
- P91006 Urmston Group PracticeManchester, United KingdomNot yet recruiting
- P92620 SSP Ince Surgery (Lower Ince)Manchester, United KingdomNot yet recruiting
- P85010 Woodlands Medical PracticeOldham, United KingdomTaking people
- P85011 CH Medical PracticeOldham, United KingdomTaking people
- P86022 Stonefield Street SurgeryRochdale, United KingdomTaking people
- P91013 Boundary House Medical CentreSale, United KingdomNot yet recruiting
- P91021 Firsway Health CentreSale, United KingdomNot yet recruiting
- P87027 Langworthy Medical PracticeSalford, United KingdomTaking people
- P88632 Stockport Medical GroupStockport, United KingdomNot yet recruiting
- P87016 The Sides Medical CentreSwinton, United KingdomTaking people
- P87025 The Lakes Medical PracticeSwinton, United KingdomTaking people
- Y02322 SSP Leigh Family PracticeWigen, United KingdomNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Eli Lilly and Company
- Trial code
- NCT07247084
- Record updated
- 9 September 2026
- Original description
The purpose of this study is to evaluate tirzepatide within a real-world setting to assess body weight loss and incidence of type 2 diabetes in adults without diabetes who have obesity and at least one weight-related comorbid condition.Read full original descriptionShow less
A Phase 4 Multicenter, Randomized, Open-Label, Interventional Study With Pragmatic Elements Investigating the Effectiveness of Tirzepatide Once Weekly Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes in a Real-World Setting
The purpose of this study is to evaluate tirzepatide within a real-world setting to assess body weight loss and incidence of type 2 diabetes in adults without diabetes who have obesity and at least one weight-related comorbid condition.
Eligible participants must be registered patients at a participating site. Participation in the study will last about 260 weeks.
Inclusion: Have a body mass index ≥30 and ≤34.9 kilogram per square meter (kg/m2); Have an increased waist to height ratio (defined by >0.5); Have at least one weight related comorbid condition; Have had at least one attempt to lose weight with lifestyle intervention (diet and physical activity).
Exclusion: Have had a change in body weight of greater than 5 kilograms (11 pounds) within 90 days prior to screening; Have type 1 diabetes, type 2 diabetes, or any other types of diabetes.