Testing a social thinking test in people with early Huntington disease
Checks a social cognition test in adults with early Huntington disease.
Key facts
- Who runs it
- Region Skane
- Where
- Lund, SwedenSee the site
- Trial code
- Registry title
- Evaluation of Three Tests to Assess Social Cognition in Huntington Disease
- Status
- Recruiting
- People taking part
- 40 people, planned
- Started
- 1 Dec 2025
- Expected to end
- 1 Sept 2027
- Type of study
- Observational, 2 groups
- Record updated
- 11 March 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with early Huntington disease, and for a control group without Huntington disease. It tests a way to measure social thinking.
- Age
- 18 Years to 75 Years
- Sex
- All sexes can join.
- Disease stage
- Early Huntington disease (clinical diagnosis of Huntington disease).
- Biomarker or test result
- People with Huntington disease need a CAG repeat of 40 and more. The control group needs no heritage of Huntington disease or a negative pre-symptomatic gene test.
Main reasons for not taking part
- Dementia, or MOCA below 19, or MMSE below 19
- Other neurological disorders
- Ongoing psychosis
- Ongoing alcohol or drug addiction
- Other native language than Swedish
The registry criteria, word for word
Show all 10 criteriaShow less
Who can take part
- Clinical diagnosis of HD
- CAG repeat: 40 and more
- No heritage of HD or negative pre-symptomatic HD gene test
Who cannot take part
- Ongoing alcohol/drug addiction
- Dementia or MOCA<19, The Mini Mental State Examination (MMSE) <19
- Other neurological disorders
- Participants in both groups are excluded from the study if any of the following criteria apply:
- Ongoing psychosis
- Other native language than Swedish
- Severe problems with vision and hearing
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Where in Sweden
- Skåne University Hospital, Region SkåneLund, SwedenContact: Isak Halling, MScTaking people
About the trial
What the trial wants to find out
The goal of this observational study is to learn about the usefulness of a test of social functioning in persons with Huntington disease. Huntington disease affects motor function, psychological well-being and cognitive functions ("thinking abilities" such as paying attention, remembering and solving problems). It is also believed to affect important social functions, including the ability to understand others' intentions and emotions (social cognition). The test of interest in this study is called The Double Movie for the Assessment of Social Cognition-Multiple Choice (DMASC-MC) and will be compared to two other similar and well-known tests. The main question which the study aims to answer is:
Read full original descriptionShow less
• Is DMASC-MC a useful tool for detecting problems with social functioning in adult persons with early Huntington disease? In the study, participants will meet with a medical doctor and a psychologist for assessment of different symptoms related to Huntington disease, including social functioning. Better methods for identifying problems with social functioning could help persons with Huntington disease and their families in mainly two ways. Firstly, it could increase their understanding of how the disease has affected them. Secondly, a better understanding of these problems could lead to better recommendations and interventions from medical teams, which would also benefit persons with Huntington disease and families.
The 2 groups in the trial
- Huntington disease
Participants with early Huntington disease
- Controls
Participants with no heritage of HD or negative pre-symptomatic HD gene test
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- The Social-HD Study: A Cross-Sectional Observational Study of Social Cognition in Early Huntington Disease
- Plain-language title
- Testing a social thinking test in people with early Huntington diseaseGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT07253038, who can take part
- Record updated
- 11 March 2026