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Tests air quality information in asthma action plans for children

Tests adding air quality index information to asthma plans in children with asthma.

Plain-language title generated from the registry record
Registry title: Pollution Intervention to Impact Kids Asthma Study

Key facts

Where
Pittsburgh, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 8 and 17 years old?

Source: NCT07261423, who can take part

Where in United States

  • UPMC Children's Hospital of PittsburghPittsburgh, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
University of Pittsburgh
Trial code
NCT07261423
Record updated
27 February 2026
Original description
The goal of this clinical trial is to learn if adding Air Quality Index (AQI) information to asthma action plans works to improve asthma outcomes in children. It will also learn about children with asthma who report being more sensitive to outdoor air pollution. The main questions it aims to answer are:Read full original descriptionShow less

Pollution Intervention to Impact Kids Asthma Study

The goal of this clinical trial is to learn if adding Air Quality Index (AQI) information to asthma action plans works to improve asthma outcomes in children. It will also learn about children with asthma who report being more sensitive to outdoor air pollution. The main questions it aims to answer are:

* Does adding either information about the EPA-AQI or commercial AQI improve asthma outcomes over time? * Are there changes in nasal gene expression in children with asthma who report they are more sensitive to outdoor air pollution?

Researchers will compare EPA-AQI and the commercial-AQI groups to a control group to either AQI works to improve asthma.

Participants will:

* Receive standardized outdoor air pollution education and an asthma action plan * Provide nose and blood specimens * Have visits every 4 weeks for 48 weeks, 10 will be conducted by telephone calls and 3 visits will be in person.

Inclusion: A healthcare provider diagnosis of persistent asthma (Steps 2-5 as defined by US guidelines) or intermittent asthma (Step 1) + at least one severe asthma exacerbation (defined by American Thoracic Society (ATS)/European Respiratory Society (ERS) criteria as requiring at least 3 days of systemic steroids or an Emergency Department/Urgent Care visit requiring systemic steroids) in the prior 12 months; Home access to a smartphone or internet; Primary residence in Allegheny County, PA; One participant per household; Age 8 -17 years; Healthcare provider evaluation for asthma in the prior year.

Exclusion: Use of intranasal or oral/intramuscular/intravenous corticosteroids 4 weeks prior to randomization; Diagnosis of other active chronic respiratory diseases (e.g., cystic fibrosis, bronchopulmonary dysplasia, etc.); Neuromuscular disorder; Chronic disorder limiting independent ambulation (e.g., spastic quadriplegia, etc.); Cyanotic heart disease; Plans to relocate from Allegheny County, PA in the next year (12 months); Current participation in another asthma intervention trial.

ClinicalTrials.gov NCT07261423