Porcine Extracellular Matrix Nerve Wrap in Neck Dissection for Head and Neck Cancer
Reason given: Dr Tam have collected the first 20 patients for interim analysis per the protocol, and are trying to get these data to perform interim analyses on these data to best understand how to move forwards.
Key facts
- Where
- Detroit, United StatesSee the site
Where in United States
- Henry Ford Health SystemDetroit, United StatesNo longer taking part
Trial details
- Who runs it
- Henry Ford Health System
- Trial code
- NCT07268092
- Record updated
- 5 December 2025
- Original description
Perform a preliminary efficacy study using the porcine extracellular matrix nerve wrap (AxoGuard Nerve Protector™, AxoGen Inc., Alachua, FL) to wrap the spinal accessory nerve (SAN) during neck dissections for head and neck cancer as it relates to postoperative shoulder function, both subjectively and objectively.Read full original descriptionShow less
Impact of Porcine Extracellular Matrix Nerve Wrap on Spinal Accessory Nerve in Patients Undergoing Neck Dissection for Head and Neck Cancer
Perform a preliminary efficacy study using the porcine extracellular matrix nerve wrap (AxoGuard Nerve Protector™, AxoGen Inc., Alachua, FL) to wrap the spinal accessory nerve (SAN) during neck dissections for head and neck cancer as it relates to postoperative shoulder function, both subjectively and objectively.
Inclusion: Patients at least 18 years old; Patients with no previous treatment of head and neck cancer; Patients with no prior neck surgeries; Patients undergoing level IIA and IIB neck diss.
Exclusion: Patients with previously treated head and neck cancers; Patients with previous neck surgery unrelated to head and neck cancer; Patients allergic to porcine products or with religious/cultural restrictions on porcine products; Patients undergoing level V neck dissection; Patients undergoing bilateral neck dissection; Patients unable to consent; Individuals who are not adults (infants, children, teenagers); Pregnant women; Prisoners.