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Tests a postbiotic supplement before colorectal cancer surgery

Tests a postbiotic supplement taken before bowel surgery in adults with colorectal cancer.

Plain-language title generated from the registry record
Registry title: Use of Preoperative Postbiotic Supplementation in Colorectal Cancer Surgery

Key facts

Where
São Paulo, BrazilSee the site

Where in Brazil

  • A.C. Camargo Cancer CenterSão Paulo, BrazilTaking people

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Trial details

Who runs it
AC Camargo Cancer Center
Trial code
NCT07268846
Record updated
8 December 2025
Original description
The treatment of colorectal cancer, in the absence of metastases, is primarily based on surgical removal. Colorectal surgery, which involves resecting part of the intestine and restoring intestinal continuity, carries a risk of complications. This study aims to evaluate whether oral supplementation with a postbiotic at a dose of 900 mg for 7 days prior to surgery reduces the rate of postoperative complications.Read full original descriptionShow less

Randomized Clinical Trial on the Use of Preoperative Postbiotic Supplementation in Colorectal Cancer Surgery

The treatment of colorectal cancer, in the absence of metastases, is primarily based on surgical removal. Colorectal surgery, which involves resecting part of the intestine and restoring intestinal continuity, carries a risk of complications. This study aims to evaluate whether oral supplementation with a postbiotic at a dose of 900 mg for 7 days prior to surgery reduces the rate of postoperative complications.

Inclusion: Individuals diagnosed with malignant neoplasm of the large intestine, specifically adenocarcinoma; Patients over 18 years of age, of both sexes; Patients who agree to participate in the study and sign the informed consent form.

Exclusion: Cytoreductive surgeries involving intraoperative intraperitoneal chemotherapy; Emergency or urgent surgeries; Extended surgeries for the treatment of recurrent tumors.

ClinicalTrials.gov NCT07268846