Surgical gloves to prevent nerve damage from oxaliplatin chemotherapy in colon cancer
Tests whether wearing surgical gloves prevents nerve damage from oxaliplatin in adults with colon cancer.
Plain-language title generated from the registry record
Registry title: Study to Evaluate the Use of Surgical Gloves for the Prevention of Oxaliplatin-Induced Peripheral Neuropathy
Key facts
- Where
- São Paulo, BrazilSee the site
Where in Brazil
- A.C. Camargo Cancer CenterSão Paulo, BrazilTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- AC Camargo Cancer Center
- Trial code
- NCT07285356
- Record updated
- 16 December 2025
- Original description
The primary objective of this randomized clinical trial is to assess whether the use of surgical gloves during treatment can prevent the occurrence of oxaliplatin-induced peripheral neuropathy.Read full original descriptionShow less
GLOX-PEN: Phase II Clinical Trial to Evaluate the Use of Surgical Gloves for the Prevention of Oxaliplatin-Induced Peripheral Neuropathy
The primary objective of this randomized clinical trial is to assess whether the use of surgical gloves during treatment can prevent the occurrence of oxaliplatin-induced peripheral neuropathy.
Inclusion: Patients aged 18 years or older who have provided written informed consent; Colon adenocarcinoma with high-risk stage III (pT4pN2) or stage IV; Oxaliplatin-based treatment in the context of localized or metastatic disease; Eastern Cooperative Oncology Group (ECOG) performance status of 0-1.
Exclusion: Prior treatment with paclitaxel, docetaxel or oxaliplatin; Uncontrolled diabetes; known glove allergies; Pre-existing neuropathy.