Computer-Aided Detection During Screening Colonoscopy to Lower Advanced Polyp Risk at 3 Years
Tests computer-aided detection during screening colonoscopy to see if advanced polyps become less common.
Plain-language title generated from the registry record
Registry title: Efficacy of CAD in Screening Colonoscopy to Reduce the Risk of Advanced Adenoma at 3 Years.
Key facts
- Where
- Bayonne, Brest, Carhaix-Plouguer, Charenton-le-Pont, Limoges, Marseille, Nantes, Nîmes, Paris, Pessac, Rennes, Toulouse, and Vandœuvre-lès-Nancy, FranceSee the 15 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who are having a screening colonoscopy, for example after a positive stool (FIT) test or because of a personal or family history of bowel cancer or polyps.
- Age
- Over 18 years
- Sex
- All sexes
- Disease stage
- Not asked for. People need an indication for colonoscopy as part of a screening program, after a positive FIT test, and/or for a personal or family history of colorectal cancer, or a personal history of colon adenomas or sessile serrated polyp.
Main reasons for not taking part
- Colonoscopy could not be completed
- Bowel preparation was not good enough
- A tumor found during the exam that likely needs surgery
- History of inflammatory bowel disease, a genetic risk of colorectal cancer, or major colon surgery (total or subtotal colectomy)
- Pregnant women
Read by machine on 13 November 2026.
Where in France
- CH de la côte BasqueBayonne, FranceContact: Felix GOUTORBE, MDNot yet recruiting
- CHU Brest la Cavale BlancheBrest, FranceContact: Lucille QUENEHERVE, MDNot yet recruiting
- Hôpital de CarhaixCarhaix-Plouguer, FranceContact: Rubeshen Pillay ARNACHELUM, MDNot yet recruiting
- Clinique Paris BercyCharenton-le-Pont, FranceContact: David KARSENTI, MDNot yet recruiting
- CHU de LimogesLimoges, FranceContact: Rémi COLLIN, MDNot yet recruiting
- Institut Paoli-CalmettesMarseille, FranceContact: Jean-Philippe RATONE, MDNot yet recruiting
- Clinique Jules VerneNantes, FranceContact: Bertrand BRIEAU, MDNot yet recruiting
- CHU NîmesNîmes, FranceContact: Ludovic CAILLO, MDNot yet recruiting
- APHP - Hôpital Saint AntoineParis, FranceContact: Xavier DRAY, MDNot yet recruiting
- APHP - Hôpital TenonParis, FranceContact: Antoine GUILLOUX, MDNot yet recruiting
- Aphp HegpParis, FranceContact: Guillaume PERROD, MDNot yet recruiting
- CHU Bordeaux - Hopital Haut-LevequePessac, FranceContact: Arthur BERGER, MDTaking people
- CHU de RennesRennes, FranceContact: Timothée WALLENHORST, MDNot yet recruiting
- Clinique PasteurToulouse, FranceContact: Mathieu GUIVARCH, MDNot yet recruiting
- CHRU de Nancy - Hôpital Brabois AdultesVandœuvre-lès-Nancy, FranceContact: Marion SCHAEFER, MDNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University Hospital, Bordeaux
- Trial code
- NCT07299071
- Record updated
- 24 September 2026
- Original description
The occurrence of interval cancers after colonoscopy raises the possibility of missed lesions. High- performance computer aided diagnosis (CAD) systems have been specially designed for the detection of colorectal lesions (CAD for detection is named CADe). The use of CADe improves adenoma detection in screening colonoscopy. The potential of CADe system in reducing the rate of progression to advanced polyps or interval cancer between two colonoscopies remains still uncertain.Read full original descriptionShow less
Randomized Controlled Trial Evaluating the Efficacy of CAD in Screening Colonoscopy to Reduce the Risk of Advanced Adenoma at 3 Years.
The occurrence of interval cancers after colonoscopy raises the possibility of missed lesions. High- performance computer aided diagnosis (CAD) systems have been specially designed for the detection of colorectal lesions (CAD for detection is named CADe). The use of CADe improves adenoma detection in screening colonoscopy. The potential of CADe system in reducing the rate of progression to advanced polyps or interval cancer between two colonoscopies remains still uncertain.
Inclusion: Patients over 18 years of age with indication for colonoscopy as part of a screening program, after a positive immunological (FIT) test, and/or for personal or family history of colorectal cancer and/or personal history of colonic adenomas and/or sessile serrated polyp,; Written informed consent signed; Patients covered by a health-care insurance.
Exclusion: An infiltrative tumor was diagnosed during colonoscope insertion time, not accessible to endoscopic resection and likely to require surgical management (a procedure where part of the colon may need to be removed); Personal history of inflammatory bowel disease; Personal history of genetic predisposition of CRC; Personal history of major colorectal surgery involving total or subtotal colectomy; Failed complete colonoscopy, defined by the absence of cecal intubation or identification of the terminal ileum; Inadequate bowel preparation (Boston bowel preparation score < 6, and/or least at one part of colon with score ≤ 1); Patient under guardianship or protection; Pregnant women; Not fluent in French or illiterate.