The Effectiveness of a Herbal Supplement in Osteoarthritis.
Key facts
- Who runs it
- Middlesex University
- Where
- London, United KingdomSee the site
- Trial code
- Status
- Recruiting
- People taking part
- 30 people, planned
- Started
- 5 Dec 2025
- Planned end
- Sept 2026
- Type of study
- Interventional, 2 groupsOne group gets a placebo (a dummy treatment), for comparison.
- Treatments tested
- Active treatment
- Placebo
- Record updated
- 29 January 2026
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
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Who can take part
- Aged ≥ 18
- Diagnosis of osteoarthritis in knee or hip
- Numerical Rating Scale (NRS) ≥ 4 during the most painful movement in the last 24 hours
- Lequesne's Functional Index (LFI) score ≥ 7
- Ambulant patient
Who cannot take part
- Expectation of surgery
- Use of concomitant medication able to interfere with the interventions
- Autoimmune disease such as rheumatoid arthritis, gout, lupus
- Joint trauma, joint injury, joint infection, meniscus tear, complete loss of articular cartilage
- History of the viscous or corticosteroids injections into affected joints or oral corticosteroids within last 12 months
- Allergy to one of the intervention's ingredients or NSAIDs
- Peptic ulceration and upper gastrointestinal haemorrhage
- High alcohol intake, inability to abstain from alcohol, substance abuse, history of addiction
- Tumor, cancer
- Pregnant and breastfeeding
- Abnormal renal or/and hepatic functions or altered blood chemistry
Where in United Kingdom
- Middlesex Univeristy LondonLondon, United KingdomContact: Patrycja Brodka Pedro, MScTaking people
About the trial
What the trial wants to find out
This study aims to evaluate the effectiveness and safety of a combined herbal supplement containing Boswellia serrata, Curcuma longa, and Vitis vinifera in adults with clinically diagnosed knee or hip osteoarthritis.
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The primary objective is to determine whether the supplement improves osteoarthritis-related symptoms.
The supplement will be compared with a placebo.
Participants will:
* take the supplement and placebo for 4 weeks each, one at a time; * complete validated questionnaires (6 times online) * perform three performance-based physical tests (6 times online) * provide a urine sample
The 2 groups in the trial
- Active TreatmentTreatment being tested
Dietary supplement containing standardised herbal extracts of Boswellia Serrata (525 mg), Curcuma Longa (150 mg), Vitis vinifera (75 mg)
- PlaceboPlacebo, for comparison
Dietary supplement placebo containing no standardised herbal extracts or other active ingredients.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Effectiveness of a Herbal Supplement Containing Boswellia Serrata, Curcuma Longa, and Vitis Vinifera in Patients With Osteoarthritis.
- Record updated
- 29 January 2026