Osteoarthritis trials in United Kingdom

In United Kingdom 27 Also abroad 848

27 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Exploring Factors Linked to Worsening Over Time in People With Early-stage Knee Osteoarthritis and Those With Prior Proven Acute Knee Injury.
Where
London
Age
18 years and over
People
200
Run by
Imperial College London
See details and how to joinNCT07833488
Phase 3Taking people
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
Where
Bristol, Glasgow, London, Newcastle, Penzance, Rotherham, Sheffield, York
Age
18 years and over
People
900 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07353931 · EU 2025-523768-19-00
No phaseTaking people
The Medacta International SMS Post-Marketing Surveillance Study
Where
Epsom
Age
18 years to 75 years
People
550 worldwide
Run by
Medacta International SA
See details and how to joinNCT02748408
No phaseTaking people
Total Versus Robotic Assisted Unicompartmental Knee Replacement
Where
Edinburgh
Age
50 years to 75 years
People
159
Run by
NHS Lothian
See details and how to joinNCT05290818
No phaseTaking people
Exactech Shoulder Post Market Clinical Follow-up Study
Where
Bath, Bedford, Ipswich, Leicester, Manchester, Nottingham, Reading, Yeovil
Age
21 years and over
People
20,000 worldwide
Run by
Exactech
See details and how to joinNCT05603728
No phaseTaking people
Manual Arthroplasty Versus VELYS Robotic-Assisted Solution Functional Alignment Arthroplasty for Knee Osteoarthritis
Where
Glasgow
Age
18 years and over
People
346
Run by
Golden Jubilee National Hospital
See details and how to joinNCT07551856
No phaseTaking people
Perform Humeral System Study
Where
Wigan
Age
18 years and over
People
300 worldwide
Run by
Stryker Trauma and Extremities
See details and how to joinNCT05067543
No phaseTaking people
OSTEOMICS: Identifying Regulators of Bone Homeostasis
Where
London
Age
18 years to 110 years
People
2,000
Run by
Relation Therapeutics
See details and how to joinNCT05732870
No phaseTaking people
The ACTIVE Trial: A Prospective Randomised Control Trial Of The H1 Implant Versus Total Hip Replacement
Where
Bournemouth, Coventry, Truro
People
200
Run by
Embody Orthopaedic Limited
See details and how to joinNCT06162195
No phaseTaking people
Feasibility of Good Boost+ for Adults Awaiting Total Knee Replacement
Where
London
Age
18 years and over
People
48
Run by
King's College Hospital NHS Trust
See details and how to joinNCT07532785
No phaseNot yet taking people in United Kingdom
The Efficacy and Safety Study of 2107 Injection in Subjects With Mild to Moderate Knee Osteoarthritis
Where
Glasgow
Age
40 years to 80 years
People
286 worldwide
Run by
BioRegen Biomedical (Changzhou) Co., Ltd
See details and how to joinNCT07746843
No phaseTaking people
Clinical Outcomes Study of the Nexel Total Elbow
Where
Wigan
Age
18 years and over
People
134 worldwide
Run by
Zimmer Biomet
See details and how to joinNCT02469662
No phaseTaking people
Developing Allogeneic Musculoskeletal Therapies
Where
Oswestry
People
325
Run by
Keele University
See details and how to joinNCT06167928
No phaseEnrolling by invitation
Long-term Follow up of the Stability 1 Trial
Where
Coventry
Age
14 years to 25 years
People
510 worldwide
Run by
Western University, Canada
See details and how to joinNCT06885372
No phaseTaking people
Evaluation of the PHENO4U Data Platform in Patients Undergoing Total Knee Arthroplasty
Where
Nottingham
Age
18 years and over
People
600 worldwide
Run by
Aesculap AG
See details and how to joinNCT05302934
No phaseTaking people
Mako Cementless TKA vs Mako Cemented TKA
Where
London
Age
18 years and over
People
120
Run by
University College, London
See details and how to joinNCT06929871
No phaseTaking people
Return to Golf After Orthopaedic Surgery
Where
Edinburgh
Age
18 years and over
People
432 worldwide
Run by
Hospital for Special Surgery, New York
See details and how to joinNCT05675618
No phaseTaking people
The Effectiveness of a Herbal Supplement in Osteoarthritis.
Where
London
Age
18 years and over
People
30
Run by
Middlesex University
See details and how to joinNCT07324746
No phaseTaking people
Does Surgical Treatment of Cartilage Defects Prevent Osteoarthritis in Later Life?
Where
Oswestry
People
650
Run by
Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
See details and how to joinNCT07320118
Phase 1Taking people
FiH Safety and Feasibility Study Assessing Intra-articular Administration of aeGF in Patients With Knee Osteoarthritis
Where
Oxford
Age
40 years and over
People
15
Run by
Scarcell Therapeutics S.A.S.
See details and how to joinNCT06690710
No phaseNot yet taking people in United Kingdom
Gait in Fixed Or Rotating Cementless Total Knee Arthroplasties
Where
Belfast
Age
18 years to 65 years
People
90
Run by
Belfast Health and Social Care Trust
See details and how to joinNCT06483178
No phaseNot yet taking people in United Kingdom
IMProving Outcomes With ACT After Knee Surgery
Where
Belfast
Age
18 years to 100 years
People
50
Run by
Belfast Health and Social Care Trust
See details and how to joinNCT06483191
No phaseTaking people
Movement Dynamics of Knee Osteoarthritis and Total Knee Replacement
Where
Portsmouth
Age
40 years to 85 years
People
36
Run by
University of Portsmouth
See details and how to joinNCT06829433
No phaseTaking people
Nerve Composition of Human Lumbar Dorsal Primary Rami and Its Medial Branch
Where
Aberdeen
Age
18 years and over
People
20
Run by
University of Aberdeen
See details and how to joinNCT05091112
No phaseTaking people
Genicular Artery Embolisation for Knee Osteoarthritis II
Where
Reading
Age
45 years and over
People
110
Run by
Varian, a Siemens Healthineers Company
See details and how to joinNCT05423587