A Nordic version of the Crohn's disease exclusion diet for children
Tests a Nordic diet adaptation in children with Crohn's disease.
Plain-language title generated from the registry record
Registry title: Modified vs Standard CDED: Evaluation of a Nordic Adaptation of Nutritional Therapy in Paediatric Crohn's Disease
Key facts
- Where
- Gothenburg, Malmö, and Skövde, SwedenSee the 3 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 6 and 18 years old?
Source: NCT07334340, who can take part
Where in Sweden
- Queen Silvia's Children's and Adolescent HospitalGothenburg, SwedenNo longer taking part
- Skånes University HospitalMalmö, SwedenNo longer taking part
- Skaraborg Hospital Skövde, Pediatric ClinicSkövde, SwedenNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Vastra Gotaland Region
- Trial code
- NCT07334340
- Record updated
- 12 January 2026
- Original description
The primary aim of this clinical trial is to evaluate the clinical effectiveness of the Nordic Crohn's Disease Exclusion Diet (Nordic CDED) in children with Crohn's disease, measured by remission rates, and to compare these outcomes with those reported for the original CDED in similar pediatric populations and study designs.Read full original descriptionShow less
Modified vs Standard Crohn´s Disease Exclusion Diet: Evaluation of a Nordic Adaptation of Nutritional Therapy in Paediatric Crohn's Diseas
The primary aim of this clinical trial is to evaluate the clinical effectiveness of the Nordic Crohn's Disease Exclusion Diet (Nordic CDED) in children with Crohn's disease, measured by remission rates, and to compare these outcomes with those reported for the original CDED in similar pediatric populations and study designs.
The secondary objectives are to assess whether the Nordic CDED can facilitate greater individualization of the diet, improve treatment adherence, and enhance quality of life.
The study seeks to answer the following key questions:
* Does the Nordic CDED achieve the same clinical effectiveness as the original CDED? * Does the Nordic CDED improve adherence and quality of life in children with Crohn's disease? To address these questions, researchers will compare outcomes from children following the Nordic CDED with published results from similar studies of the original CDED, as well as with patients who were not treated with a dietary intervention.
Participant Involvement:
* Follow the Nordic CDED for 20 weeks. * Attend clinic visits at weeks 2, 8, 14, 20, and 24 for checkups and tests. * Report adherence to the diet through food records. * Report quality of life at the beginning and end of the study
Inclusion: Children aged 6-18 years with recent (<36 months) mild-to-severe CD diagnosis (defined as Paediatric Crohn's Disease Activity Index [PCDAI] 15-47.5); Evidence of active inflammation (C-reactive protein [CRP] ≥ 0.5 mg/dL, erythrocyte sedimentation rate [ESR] ≥ 20 mm/h, and/or faecal calprotectin [FCP] ≥ 200 mg/g during screening); Stable use of medication other than steroids.
Exclusion: Use of systemic corticosteroids; Eating disorders,; Active perianal disease; Documented cow's milk protein allergy; Diabetes, celiac disease and/or psychosocial difficulties; Active extraintestinal manifestations; Positive stool cultures for pathogens, parasites, or Clostridioides difficile; Fever >38.3°C.