Taking people in United StatesNo phase

Pistachio snacks and a health session for midlife women with poor sleep

Tests pistachio snacking plus a health education session in midlife women sleeping poorly.

Key facts

Who runs it: The University of Texas Medical Branch, Galveston
Where: Galveston, United StatesSee the site
Trial code: NCT07337915
Registry title: Improving Sleep In Midlife Women
Status: Recruiting
People taking part: 72 people, planned
Started: 16 Feb 2026
Expected to end: 31 Aug 2027
Type of study: Interventional, 3 groups
Treatments tested: HealthyHabits1
HealthyHabits2
Snack 2
Snack 1
Record updated: 3 March 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for women aged 45-65 around or after menopause who sleep poorly. They will eat a study snack (pistachios or potato chips) for about one month and have one health education session.

Age: 45 to 65 years
Sex: Women only
Disease stage: Late peri-menopause (no period for 60 days, STRAW score of -1) or early post-menopause (more than 12 months since the last period, STRAW score of +1a, +1b or +1c). Poor sleep quality (Pittsburgh Sleep Quality Index score > 5).
Earlier treatment: No use, now or in the last 3 months, of medicines that may affect sleep, such as systemic steroids, anabolic steroids, growth hormone or immunosuppressants. No change in antidepressant use or dose in the last 3 months. No GLP-1 RA medicines.

Main reasons for not taking part

Pregnancy or breastfeeding
Untreated other sleep disorders, such as narcolepsy, shift work sleep problems, restless leg syndrome or obstructive sleep apnea
Severe mental health problems recently, such as a suicide attempt or psychiatric hospital stay in the past 3 years
Cancer treated in the past 3 years, except basal cell carcinoma
Allergy to tree nuts, being on a weight-loss or weight-gain diet, or alcohol or drug use disorder in the past 12 months

The registry criteria, word for word

Show all 17 criteriaShow less

Who can take part

All races and ethnic backgrounds
Between the ages of 45-65 years old
Women who meet STRAW staging criteria for late peri-menopause (STRAW score of -1) defined as interval of amenorrhea of 60 days OR meet STRAW staging criteria for early post-menopause (STRAW score of +1a, +1b or +1c) defined as >12 months since last menstrual period
History of poor sleep quality (Pittsburgh Sleep Quality Index score > 5)
Able and willing to provide informed consent
Access to an electronic device with teleconferencing capabilities (Teams, etc)
Willing to consume study intervention
Fluent (able to read and write) in English

Who cannot take part

Recent (within the last 3 months) or current use of any prescription or over the counter medications that may impact sleep quality:; including, systemic steroids, anabolic steroids, growth hormone, immunosuppressants, psychotherapy); recent (within the last 3 months) change in antidepressant medication useage or dosage
Current adherence to a weight-loss or weight-gain diet or use of GLP-1 RA medications
Untreated comorbid sleep disorders that are no known to be responsive to the behavioral interventions: These sleep disorders include but are not limited to narcolepsy, circadian rhythm disorder/shift work, restless leg syndrome, periodic leg movement disorder, obstructive sleep apnea
Evidence of recent severe mental health disorders (e.g., suicide attempt or psychiatric hospitalization in past 3 years) that would, in the opinion of the investigator, affect sleep and/or make it difficult for the participant to the investigators instructions
Recent (within past 3 years) treated cancer other than basal cell carcinoma
Active or recent (within the past 12 months) alcohol or substance use disorder
Allergy to study intervention (tree nuts)
Any other condition or event considered exclusionary by study PI
Pregnancy or lactation

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

Are you between 45 and 65 years old?

Where in United States

University of Texas Medical BranchGalveston, United StatesContact: Paula Skinkis, M.EdTaking people

About the trial

What the trial wants to find out

This study purpose of this study to see how consuming pistachios and completing a health intervention session a study therapist may improve sleep health in midlife women with poor sleep. Participants in this study will be asked to consume a study snack for about one month, complete a health education session with a study therapist and record information about their sleep. At baseline and after the intervention we will collect information about sleep, alertness, body composition, and blood lipids.

The 3 groups in the trial

Snack 1 + HeathyHabits1Other group
Participants in this arm will consume 2 servings of potato chips per day for 30 days. They will also meet once with a study therapist for discussion and suggestions to improve healthy habits (e.g.,diet/nutrition, activity, sleep).
Treatment: HealthyHabits1 and Snack 1
Snack 2 + HealthyHabits2Other group
Participants in this arm will consume 2 servings of pistachios for 30 days. They will also meet once with a study therapist for discussion and suggestions to improve sleep habits.
Treatment: HealthyHabits2 and Snack 2
Snack 2 + HealthyHabits1Other group
Participants in this arm will consume 2 servings of pistachios per day for 30 days. They will also meet once with a study therapist for discussion and suggestions to improve healthy habits (e.g.,diet/nutrition, activity, sleep).
Treatment: HealthyHabits1 and Snack 2