Pistachio Snacking and How the Body Uses Fuel in Adults With Overweight

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults aged 25-45 who are overweight or obese, sleep poorly, are otherwise healthy and do little exercise. It tests whether eating pistachios as a snack changes how the body uses fuel.

Age

25-45 years

Sex

Men and women can join.

Disease stage

Overweight or obese (BMI 25.0-34.9 kg/m²), otherwise healthy, with poor sleep quality.

Earlier treatment

No prior treatment is asked for. People cannot be on a diet that is restrictive or leaves out certain food groups or types.

Biomarker or test result

Pittsburgh Sleep Quality Index of 5 or higher. Not meeting weekly physical activity recommendations: under 150 min moderate exercise, under 75 min vigorous exercise and under 2 days of strength training.

Main reasons for not taking part

• Allergy to nuts, especially tree nuts
• Has a pacemaker
• Known metabolic or endocrine disorder, heart or blood vessel disease, nerve, muscle or bone disorder
• Cancer or cancer treatment within the past year
• Pregnant or planning pregnancy, pregnant within the last year, breastfeeding, or known to be perimenopausal

The registry criteria, word for word

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

• Are you between 25 and 45 years old?YesNo

What the trial wants to find out

The purpose of this study is to evaluate the effects of pistachio snacking on metabolic flexibility (at rest, during exercise, and in post-exercise recovery) in healthy overweight and obese adults. Secondary goals include evaluating effects on changes in diet quality, sleep characteristics, physical activity, and hormonal health in women. In randomized order, participants will complete four days of pistachio snacking and four days of normal dietary habits (control). For both conditions, primary outcomes of resting substrate metabolism, metabolic flexibility during exercise, and post-exercise substrate metabolism will be measured pre-post intervention via indirect calorimetry. Secondary outcome of diet quality (kcal, carb, fat, protein) will be measured pre-post intervention via diet log. Exploratory outcomes of daily physical activity (steps, intensity), nightly sleep characteristics (quantity, quality, latency, efficiency), and daytime sleepiness and hunger.

The 2 groups in the trial

• PistachioTreatment being tested

  Four days of pistachio snacking, to be consumed mid-morning (1oz; 9-11am), mid-afternoon (1oz; 2-4pm), and pre-sleep (0.5 oz; within 1hr of bedtime), while otherwise maintaining normal dietary habits. An addition snack will be consumed post-exercise (0.5oz).

• ControlNo study treatment, for comparison

  Maintain normal dietary habits for four days.