Tracking Speech and Breathing Changes in Spanish-Speaking People With ALS
Studies smartphone speech and breathing recordings in Spanish speakers with amyotrophic lateral sclerosis.
Plain-language title generated from the registry record
Registry title: Digital Speech Markers for Monitoring ALS in Spanish Speakers
Key facts
- Where
- Fort Lauderdale, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 90 years old?
Source: NCT07341334, who can take part
Where in United States
- Cathy J Husman ALS Center at Nova Southeastern UniversityFort Lauderdale, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Nova Southeastern University
- Trial code
- NCT07341334
- Record updated
- 3 August 2026
- Original description
The goal of this observational study is to learn how speech and breathing change over time in Spanish-speaking individuals with amyotrophic lateral sclerosis (ALS) compared to age- and gender-matched individuals without ALS.Read full original descriptionShow less
Developing Digital Speech Biomarkers of Bulbar Disease Decline in Spanish-Speaking Persons With Amyotrophic Lateral Sclerosis
The goal of this observational study is to learn how speech and breathing change over time in Spanish-speaking individuals with amyotrophic lateral sclerosis (ALS) compared to age- and gender-matched individuals without ALS.
The main questions it aims to answer are:
Can speech and breathing measures collected through a smartphone application serve as reliable digital biomarkers to track bulbar disease decline in Spanish-speaking people with ALS?
How do these measures differ between individuals with ALS and those without ALS?
Researchers will compare Spanish-speaking participants with ALS to age- and gender-matched healthy controls to see if specific speech and breathing features can identify or predict bulbar decline.
Participants will:
Use a Spanish-language smartphone application to record speech and breathing tasks over time.
Complete assessments of speech, breathing, and functional abilities (e.g., ALS Functional Rating Scale).
Provide data that will be compared to caregiver reports and clinical outcomes to validate new digital biomarkers.
Inclusion: diagnosis of definite ALS; monolingual or first language Spanish speaker; literate in Spanish; ALS Functional Rating Scale speech score of ≧2.
Exclusion: no diagnosis of concomitant respiratory disease such as COPD, emphysema, or current TOB use.