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Taking people in United StatesPhase 3

Open Label Study to Investigate the Safety and Efficacy of Ponesimod in Moderate-to-Severe Chronic Plaque Psoriasis

Key facts

Where
Fremont, Glendale, Indianapolis, Miami, Portsmouth, Rochester, San Antonio, Spokane, Webster, and Wilmington, United StatesSee the 10 sites
Phase
Phase 3

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 65 years old?

Source: NCT07362017, who can take part

Where in United States

  • FremontFremont, United StatesTaking people
  • GlendaleGlendale, United StatesTaking people
  • IndianapolisIndianapolis, United StatesTaking people
  • MiamiMiami, United StatesTaking people
  • PortsmouthPortsmouth, United StatesTaking people
  • RochesterRochester, United StatesTaking people
  • San AntonioSan Antonio, United StatesTaking people
  • SpokaneSpokane, United StatesTaking people
  • WebsterWebster, United StatesTaking people
  • WilmingtonWilmington, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Vanda Pharmaceuticals
Trial code
NCT07362017
Record updated
22 September 2026
Original description
An open label study to investigate the safety and efficacy of ponesimod in participants with moderate-to-severe chronic plaque psoriasisRead full original descriptionShow less

A Multicenter, Open Label Study to Investigate the Safety and Efficacy of Ponesimod in the Treatment of Moderate-to-Severe Chronic Plaque Psoriasis

An open label study to investigate the safety and efficacy of ponesimod in participants with moderate-to-severe chronic plaque psoriasis

Inclusion: Male and female subjects aged 18-65 years, inclusive; BMI >18 and <40; Minimum affected BSA of 10%; PASI score ≥ 12; PGA ≥ 3; Diagnosed with moderate-to-severe plaque psoriasis.

Exclusion: History of an allergic reaction or known and/or significant sensitivity to study drug; Diagnosis of generalized erythrodermic, generalized pustular (von Zumbusch), guttate, or palmoplantar psoriasis.

ClinicalTrials.gov NCT07362017