Looking for Home Sources of Mycobacteria Infection in People with Cystic Fibrosis
Checks household water and surroundings of people with cystic fibrosis, with and without mycobacteria infection.
Plain-language title generated from the registry record
Registry title: Environmental Reservoirs of Non-tuberculous Mycobacteria in Cystic Fibrosis Households
Key facts
- Where
- Borstel and Essen, GermanySee the 2 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people with cystic fibrosis, both with and without a non-tuberculous mycobacteria (NTM) infection. Samples from their homes will be tested.
- Age
- No age limit. Children can join with a legal guardian's consent.
- Sex
- All sexes can join.
- Disease stage
- Confirmed cystic fibrosis. If a person has an NTM infection, it must be diagnosed by ATS/IDSA criteria.
- Biomarker or test result
- For people with an NTM infection, a clinical NTM isolate must be available.
Main reasons for not taking part
- Cannot give informed consent
- Refuses to take part
- Withdraws consent
Read by machine on 9 November 2026.
Where in Germany
- National and WHO-Supranational Reference Center for Mycobacteria, Research Center Borstel, Leibniz Lung CenterBorstel, GermanyTaking people
- Klinik für Pneumologie, Universitätsklinikum EssenEssen, GermanyNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Research Center Borstel
- Trial code
- NCT07369414
- Record updated
- 19 August 2026
- Original description
This multicenter, non-interventional case-control study investigates whether household environmental reservoirs, particularly water systems, are associated with non-tuberculous mycobacterial (NTM) infections in people with cystic fibrosis (CF). Environmental samples from the homes of CF patients with and without NTM infection will be analyzed and genetically compared with available clinical isolates, alongside assessment of environmental risk factors, to improve understanding of exposure pathways and inform future prevention strategies.Read full original descriptionShow less
Environmental Reservoirs of Non-tuberculous Mycobacteria in Cystic Fibrosis Households: A Case-control Study of Exposure Risk at Home
This multicenter, non-interventional case-control study investigates whether household environmental reservoirs, particularly water systems, are associated with non-tuberculous mycobacterial (NTM) infections in people with cystic fibrosis (CF). Environmental samples from the homes of CF patients with and without NTM infection will be analyzed and genetically compared with available clinical isolates, alongside assessment of environmental risk factors, to improve understanding of exposure pathways and inform future prevention strategies.
Inclusion: Confirmed diagnosis of cystic fibrosis (CF); No age restriction (including minors with consent from legal guardians); Written informed consent to participate in the study (or consent provided by a legal guardian for minors); In the case of an NTM infection: diagnosis according to ATS/IDSA criteria and availability of a clinical NTM isolate.
Exclusion: Lack of capacity to provide informed consent, refusal to participate, or withdrawal of informed consent.