Cystic fibrosis trials in Germany

In Germany 13 Also abroad 188

13 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients With Cystic Fibrosis
Where
Berlin, Potsdam
Age
18 years and over
People
64 worldwide
Run by
SpliSense Ltd.
See details and how to joinNCT06429176
Phase 2Taking people
A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Adult Study Participants With Non-Cystic Fibrosis Bronchiectasis
Where
Berlin, Cologne, Hanover
Age
18 years to 80 years
People
300 worldwide
Run by
UCB Biopharma SRL
See details and how to joinNCT07720375 · EU 2026-525524-18-00
No phaseTaking people
Long-term Evaluation of the SIMEOX Device at Home in Non-cystic Fibrosis Bronchiectasis
Where
Aachen, Lübeck, München
Age
18 years and over
People
468 worldwide
Run by
Physio-Assist
See details and how to joinNCT06487273
Phase 2Not yet taking people in Germany
A Study to Access Activity and Safety with SAR445399 Compared with Placebo in Participants Aged 18 to 80 Years of Age with Non-Cystic Fibrosis Bronchiectasis
Where
Bendorf, Berlin, Essen, Frankfurt am Main
Age
18 years and over
People
41 worldwide
Run by
Sanofi-Aventis Recherche & Developpement
See details and how to join2025-523403-29-00
Phase 2Taking people
Dose Range Finding, Efficacy, and Safety Study of Nebulized CSL787 in Adults With Non-cystic Fibrosis Bronchiectasis (NCFB)
Where
Ahrensburg, Berlin, Dresden, Frankfurt am Main, Frankfurt Am Main, Jena, Luebeck, Mainz, Munich
Age
18 years to 85 years
People
180 worldwide
Run by
CSL Behring
See details and how to joinNCT07048262 · EU 2024-518821-13-00
Phase 2Taking people
Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients with Cystic Fibrosis
Where
Berlin, Munich, Potsdam
Age
18 years and over
People
30 worldwide
Run by
Splisense Ltd.
See details and how to join2024-511184-28-00
No phaseTaking people
Environmental Reservoirs of Non-tuberculous Mycobacteria in Cystic Fibrosis Households
Where
Borstel, Essen
People
120
Run by
Research Center Borstel
See details and how to joinNCT07369414
Phase 2Not yet taking people in Germany
Safety and Efficacy of VX-828/Deutivacaftor Combination Therapy With and Without Tezacaftor in Subjects With Cystic Fibrosis
Where
Berlin, Essen, Mainz, Munich, Potsdam
Age
18 years and over
People
80 worldwide
Run by
Vertex Pharmaceuticals Inc.
See details and how to join2025-523400-72-00
Phase 3Enrolling by invitation
Evaluation of Long-Term Safety and Efficacy of Vanzacaftor/Tezacaftor/Deutivacaftor in Cystic Fibrosis Participants 1 Year of Age and Older
Where
Berlin, Essen, Hanover
Age
1 year to 17 years
People
174 worldwide
Run by
Vertex Pharmaceuticals Incorporated
See details and how to joinNCT05844449 · EU 2022-503081-74-00
No phaseTaking people
Modulate-CF: Cystic Fibrosis Transmembrane Regulator (CFTR) Biomarker Study to Evaluate the Rescue of Mutant CFTR in Patients With Cystic Fibrosis Treated With CFTR-modulators
Where
Berlin, Giessen, Hanover, Heidelberg
Age
6 months and over
People
500
Run by
Charite University, Berlin, Germany
See details and how to joinNCT04732910
No phaseTaking people
Characterization of Antibacterial Antibodies in Patients With Cystic Fibrosis
Where
Cologne
Age
18 years and over
People
75
Run by
University Hospital of Cologne
See details and how to joinNCT04700358
No phaseTaking people
Longitudinal Observational Study on the Course of Cystic Fibrosis Lung Disease in Patients Following Newborn Screening
Where
Giessen, Hanover, Heidelberg, Lübeck
People
200
Run by
Heidelberg University
See details and how to joinNCT02270476
No phaseTaking people
Development and Validation of a Disease Specific PROM to Assess Abdominal Involvement in Patients With CF (CFAbd-Score)
Where
Brandenburg an der Havel
People
2,000
Run by
Medizinische Hochschule Brandenburg Theodor Fontane
See details and how to joinNCT03052283