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Tests a community health worker lifestyle program for Pacific Islander adults at risk

Tests a lifestyle program for Pacific Islander adults with prediabetes or heart risk.

Key facts

Who runs it
University of Hawaii
Where
Fayetteville and Honolulu, United StatesSee the 2 sites
Trial code
Registry title
To Test the Effectiveness and Implementation Approach of a 3-month PILI Pasifika Program Lifestyle Program With Components of Social Determinants of Health Activities in Real-world Settings (Clinical and Non-clinical Settings) Across 3 Years
Status
Enrolling by invitation
People taking part
400 people, planned
Started
1 May 2026
Expected to end
31 Oct 2028
Type of study
Interventional, 2 groups
Treatments tested
  • PILI (Partnership for Improving Lifestyle Intervention) Pasifika Program
Record updated
9 June 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for Native Hawaiian and Pacific Islander adults who have at least one heart or metabolic condition, such as overweight, pre-diabetes or diabetes, high blood pressure or high cholesterol, and who can do moderate physical activity.

Age
18 years or older
Sex
All sexes can join.
Disease stage
At least one self-reported condition: overweight or obesity (BMI ≥ 25), pre-diabetes or diabetes, high blood pressure, and/or high cholesterol.

Main reasons for not taking part

  • Does not identify as Native Hawaiian or Pacific Islander
  • Currently a student
  • Special dietary needs or restrictions (cultural reasons or told by a healthcare provider)
  • Pregnant women
  • Physical activity limits or restrictions told by a healthcare provider

The registry criteria, word for word

Show all 11 criteriaShow less

Who can take part

  • Self-identify as Native Hawaiian or Pacific Islander
  • 18 years of age or older
  • Have at least one of the following self-reported cardiometabolic conditions (Overweight or obesity defined as BMI ≥ 25, pre-diabetes or diabetes, high blood pressure, and/or high cholesterol)
  • Able to do a moderate level of physical activity or exercise

Who cannot take part

  • Do not have any of the following conditions (overweight/obesity, pre-diabetes/diabetes, high blood pressure, or high cholesterol)
  • Under 18 years of age
  • Do not identify as Native Hawaiian or Pacific Islander
  • Currently a student
  • Have special dietary needs/dietary restrictions (due to cultural reasons and/or told by a healthcare provider)
  • Pregnant women
  • Have physical activity limitations/restrictions (told by a healthcare provider)

Where in United States

  • National Association of Pasifika OrganizationsFayetteville, United StatesEnrolling by invitation
  • Papa Ola LokahiHonolulu, United StatesEnrolling by invitation

About the trial

What the trial wants to find out

In this study, the investigators are conducting a Type 3 hybrid effectiveness-implementation trial to evaluate the implementation of the Community Health Workers (CHW)-delivered PILI Pasifika Program (PPP) across 3 regions, the U.S. Affiliated Pacific Islands (USAPI), the continental U.S., and Hawai'i, among 400 Native Hawaiian and Pacific Islander (NHPI) participants in two settings, (clinical and non-clinical) over a 3-year period. The PPP is a 3-month lifestyle intervention that includes a Social Determinants of Health (SDOH) component and was NHPI-adapted from the Diabetes Prevention Program's Lifestyle Program, renamed to the PILI Lifestyle Program (PLP), which demonstrated effectiveness in improving weight, blood pressure, physical activity, and diet among NHPIs. The PPP consists of 8 lifestyle lessons and 4 SDOH activities delivered over a 3-month period.

Read full original descriptionShow less

The aims of this study are threefold:

1. To evaluate the implementation of the PPP across multiple community sites using a Type 3 hybrid effectiveness-implementation design guided by established frameworks such as RE-AIM and PRISM. 2. To examine participant-level outcomes associated with PPP implementation, including changes in cardiometabolic risk factors, health behaviors, and SDOH factors from baseline to 3 and 9-month follow-up. 3. To evaluate the cost and cost-effectiveness of implementing the PPP across community settings.

The 2 groups in the trial

  • PILI Pasifika Program - Clinical SettingTreatment being tested

    Participants in this group will engage in a 3-month PILI Pasifika Program (PPP) with a trained Community Health Worker (CHW). Each week during the 3-months, participants will meet for approximately 1-1.5 hours to receive a Weekly Lesson or engage in an SDOH activity. Participants will also complete an assessment at baseline, at the 3-month program completion, and at the 9-month follow-up.

    Treatment: PILI (Partnership for Improving Lifestyle Intervention) Pasifika Program

  • PILI Pasifika Program - Community (Non-Clinical) SettingTreatment being tested

    Participants in this group will engage in a 3-month PILI Pasifika Program (PPP) with a trained Community Health Worker (CHW). Each week during the 3-months, participants will meet for approximately 1-1.5 hours to receive a Weekly Lesson or engage in an SDOH activity. Participants will also complete an assessment at baseline, at the 3-month program completion, and at the 9-month follow-up.

    Treatment: PILI (Partnership for Improving Lifestyle Intervention) Pasifika Program

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Peau o le Vasa: Accelerating the Currents of Health Advances for Pasifika People
Plain-language title
Tests a community health worker lifestyle program for Pacific Islander adults at riskGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
9 June 2026