Following people with diabetes and obesity over time through routine clinic visits
Collects health data and samples from people with diabetes or obesity over many years.
Plain-language title generated from the registry record
Registry title: Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and Adults
Key facts
- Where
- Bethesda, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 8 and 65 years old?
Source: NCT07388537, who can take part
Where in United States
- National Institutes of Health Clinical CenterBethesda, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Trial code
- NCT07388537
- Record updated
- 10 November 2026
- Original description
Background:Read full original descriptionShow less
Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and Adults
Background:
Diabetes and obesity are chronic diseases. They can affect blood flow and how the body processes nutrients, and complications over time can lead to early death. Diabetes can affect children as well as adults, but the disease seems to be more severe and to progress faster when it appears in younger people. Researchers want to understand more about how diabetes and obesity develop and change over time.
Objective:
To collect data and samples regularly from people with obesity and diabetes.
Eligibility:
People aged 8 to 65 years. They must be overweight or obese; or have high blood sugar; or have problems with how their body uses food for energy.
Design:
Participants will have additional procedures during routine care visits at the NIH clinic.
Data collected for the study will include the following:
Information from the participant s medical chart will be kept for research.
Questionnaires will ask about participant s eating habits, feelings, sleep, and substance use. They will take 30 to 60 minutes. Care providers will address any issues revealed in these surveys.
Blood, saliva, urine, and stool samples will be collected. Samples may be used for genetic tests.
Data and samples will be kept for future research.
Participants may remain in the study up to 30 years.
Exclusion: History of significant medical illnesses that the investigators feel may interfere with potential evaluations, i.e. individuals who are critically ill, unstable, or with severe organ failure that may affect/limit the endocrine evaluation and place unsustainable demands on Clinical Center or NIDDK resources; History of any medical, psychiatric, or social conditions which, in the opinion of the investigators, would make participation in this protocol not in the best interest of the participant; An individual who meets any of the following criteria will be excluded from participation in this study:; Inability or unwillingness of participant, parent/guardian, or LAR to provide informed consent.
INCLUSION CRITERIA:; In order to be eligible to participate in this study, an individual must meet all of the following criteria:; Age 8 years to 65 years; Meet at least one of the following:; Overweight/Obesity:; For participants under 18 years of age: BMI >= 85th percentile for age and sex; For participants >= 18 years of age: BMI >= 25 kg/m\^2 (>=23 kg/m\^2 for self-reported Asian race/ethnicity); Suspected or evidence of hyperglycemia:; Diagnosis of prediabetes or diabetes in medical history or by participant/guardian/Legally Authorized Representative (LAR) report, OR; Fasting blood glucose >= 100 mg/dL in medical record, OR; Postprandial blood sugar >= 140 mg/dL in medical record, OR; Hemoglobin A1c >= 5.7% in medical record.