Tests a breathing device during pulmonary rehabilitation for COPD
Tests a breathing device against a sham device in people with COPD.
Plain-language title generated from the registry record
Registry title: PEP Buddy in Pulmonary Rehabilitation
Key facts
- Where
- Cincinnati and Cleveland, United StatesSee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 89 years old?
Source: NCT07404826, who can take part
Where in United States
- Cincinnati VA Medical Center, Cincinnati, OHCincinnati, United StatesTaking people
- Louis Stokes VA Medical Center, Cleveland, OHCleveland, United StatesNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- VA Office of Research and Development
- Trial code
- NCT07404826
- Record updated
- 24 July 2026
- Original description
In this study, the investigators will test Veterans with COPD in Pulmonary Rehabilitation. Between two groups, the investigators will give one group a device that assists with breathing and symptoms and the other receives a 'sham' device which does not provide these benefits. The investigators will test to see if the symptoms and exercise capacity of the group who receives this device improves faster in Pulmonary Rehabilitation and has longer lasting benefits after the end of Pulmonary Rehabilitation.Read full original descriptionShow less
A Randomized, Sham Controlled Clinical Trial to Assess the Effectiveness of a Positive End Expiratory Device for Accelerating and Maintaining Pulmonary Rehabilitation Gains
In this study, the investigators will test Veterans with COPD in Pulmonary Rehabilitation. Between two groups, the investigators will give one group a device that assists with breathing and symptoms and the other receives a 'sham' device which does not provide these benefits. The investigators will test to see if the symptoms and exercise capacity of the group who receives this device improves faster in Pulmonary Rehabilitation and has longer lasting benefits after the end of Pulmonary Rehabilitation.
Inclusion: Veteran; Referral to Pulmonary Rehabilitation for COPD; FEV1 <80% predicted; Participants must be able to exercise on 4L/m nasal cannula O2.
Exclusion: Those with a known surgical intervention that will require a prolonged recovery in the year after enrollment; Those deemed by the study personnel to have a lung disease other than COPD impacting their daily dyspnea; Those that have a component of lung disease driven by aspiration or neurological conditions affecting the face or oropharynx; Those with a malignancy beyond Stage I or non-melanoma skin cancer; Those that are unable to perform study procedures or are unwilling or unable to use PEP Buddy; Those with a life expectancy of <1 year; Those shown shown to have memory loss of MOCA testing.