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A ketogenic diet for osteoarthritis pain in people with memory problems

Tests a ketogenic diet in people with osteoarthritis and memory problems.

Key facts

Who runs it
University of Kansas Medical Center
Where
Fairway, United StatesSee the site
Trial code
Registry title
Ketogenic Diet to Reduce Osteoarthritis Pain in MCI
Status
Not yet recruiting
People taking part
10 people, planned
Started
1 Jun 2026
Expected to end
1 Jun 2027
Type of study
Interventional
Treatments tested
  • Well-formulated ketogenic diet
Record updated
4 May 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for English-speaking adults with osteoarthritis of a major joint and mild cognitive impairment (mild memory and thinking problems). Participants follow a supervised ketogenic diet.

Age
55 Years to 75 Years
Sex
All sexes can join
Disease stage
Diagnosis of major joint osteoarthritis and a diagnosis of mild cognitive impairment.
Earlier treatment
People already following a ketogenic diet cannot join. People who had chemo- or radiation therapy for cancer in the last 2 years cannot join.

Main reasons for not taking part

  • Diabetes that needs insulin
  • Heart event within 1 year
  • Recent kidney stones
  • Diagnosis of fibromyalgia
  • A diet that does not allow a ketogenic approach, or being unable to control one's diet

The registry criteria, word for word

Show all 11 criteriaShow less

Who can take part

  • English speaking
  • Diagnosis of major joint osteoarthritis
  • Diagnosis of mild cognitive impairment

Who cannot take part

  • Diabetes that requires insulin
  • Cancer requiring chemo- or radiation therapy in the last 2 years
  • Cardiac event within 1 year
  • Recent history of renal stones
  • Diagnosis of fibromyalgia
  • Already following a ketogenic diet
  • Following a dietary pattern that does not allow for a ketogenic approach
  • Unable to control one's diet

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 55 and 75 years old?

Where in United States

  • University of Kansas Medical CenterFairway, United StatesContact: Jessica Keller, PhD, RDNNot yet recruiting

About the trial

What the trial wants to find out

Osteoarthritis and mild cognitive impairment are common conditions that share underlying biological processes related to metabolism and inflammation. This study will examine whether a well-formulated ketogenic diet influences pain, physical function, and cognitive outcomes in adults with osteoarthritis and mild cognitive impairment. Participants will follow a supervised ketogenic dietary intervention, with assessments conducted before and after the intervention to evaluate changes in symptoms and related biological markers. The goal of this study is to better understand shared mechanisms between joint pain and cognitive health and to explore whether a ketogenic dietary approach may support symptom management in these populations.

The group in the trial

  • Well-formulated ketogenic dietTreatment being tested

    This is a dietary intervention that is very low carbohydrate, higher healthy fats, and adequate protein.

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Ketogenic Diet to Reduce Osteoarthritis Pain in MCI
Plain-language title
A ketogenic diet for osteoarthritis pain in people with memory problemsGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 14 November 2026.
Fit questions
Built from NCT07417891, who can take part
Record updated
4 May 2026