Home Virtual Reality Brain-Feedback Training for Teenagers With Migraine
Tests whether home virtual reality training is workable for adolescents with migraine.
Plain-language title generated from the registry record
Registry title: A Feasibility Trial of Virtual Reality Neurofeedback for Adolescents With Migraine
Key facts
- Where
- Kansas City, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 10 and 16 years old?
Source: NCT07454798, who can take part
Where in United States
- Children's MercyKansas City, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Children's Mercy Hospital Kansas City
- Trial code
- NCT07454798
- Record updated
- 3 June 2026
- Original description
The goal of this clinical trial is to learn whether a home-based virtual reality (VR) neurofeedback program is feasible and acceptable for adolescents with migraine. The study will also explore whether the program may improve headache-related outcomes.Read full original descriptionShow less
Feasibility of Home-based Immersive Neurofeedback Self-regulation Training (INSeRT) for Youth With Migraine
The goal of this clinical trial is to learn whether a home-based virtual reality (VR) neurofeedback program is feasible and acceptable for adolescents with migraine. The study will also explore whether the program may improve headache-related outcomes.
The main questions it aims to answer are:
Is it feasible to enroll, randomize, and retain adolescents with migraine in this study?
Do participants complete the VR sessions and study procedures as intended?
Are there preliminary signals that the VR neurofeedback program may improve headache-related disability and symptoms?
Researchers will compare Immersive Neurofeedback Self-Regulation Training (INSeRT), which uses brain activity recorded from a wearable electroencephalogram (EEG) headband to guide the VR experience, to a comparison VR program that presents immersive imagery without neurofeedback or guided relaxation training.
Participants will:
Complete a 4-week baseline period that includes headache logs, questionnaires, and a laboratory EEG assessment
Be randomly assigned to one of two VR programs
Complete VR sessions at home three times per week for 4 weeks
Complete questionnaires at the end of treatment and again approximately 3 months later
Repeat the laboratory EEG assessment at the end of treatment
Inclusion: Age 10-16 years (inclusive); Diagnosis of migraine (with or without aura, or chronic migraine) by a qualified headache specialist; At least 4 migraine headaches per month; Presence of headache-free periods between migraine episodes.
Exclusion: Clinically elevated Pediatric Vestibular Symptoms Questionnaire (PVSQ) score (>0.68) or new/worsening vestibular symptoms prior to randomization; Initiation of a new migraine preventive medication within 4 weeks prior to randomization; Current participation in behavioral treatment for migraine (e.g., cognitive behavioral therapy or biofeedback); Significant physical, psychiatric, or developmental conditions that would limit ability to participate in study procedures; History of epilepsy or photosensitive seizures.