Dental cleaning and hygiene teaching for teens with obesity taking semaglutide
Tests whether dental cleaning helps teens aged 12 to 17 with obesity.
Plain-language title generated from the registry record
Registry title: MODERN-Dental: Pediatric Obesity, Cardiometabolic Risks, And Periodontal Disease
Key facts
- Where
- Lexington, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 12 and 17 years old?
Source: NCT07478653, who can take part
Where in United States
- University of KentuckyLexington, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Oelisoa Andriankaja
- Trial code
- NCT07478653
- Record updated
- 8 October 2026
- Original description
The goal of this clinical trial is to assess whether adjunctive dental cleaning can enhance the effects of semaglutide in children with obesity. The main question[s] it aims to answer [is/are]:Read full original descriptionShow less
MODERN-Dental: Pediatric Obesity, Cardiometabolic Risks, And Periodontal Disease: Effects Of Semaglutide Treatment
The goal of this clinical trial is to assess whether adjunctive dental cleaning can enhance the effects of semaglutide in children with obesity. The main question[s] it aims to answer [is/are]:
if dental cleaning will improve both oral health and metabolic outcomes beyond the effects of semaglutide alone.
Participants will receive either dental cleaning and oral hygiene instruction or oral hygiene instruction alone.
Inclusion: participants from the ongoing Mitigation of Cardiovascular Disease Risks in Children with Extreme Obesity (MODERN) study (NCT06967389); Class 2 or 3 obesity (BMI =120% of the 95th percentile for age and sex).
Exclusion: Use of any anti-inflammatory medication (other than steroids) within 1 month prior to enrollment; Currently taking medications that could influence the characteristics or response to periodontal treatment (e.g., use of immunosuppressants or steroids); Local or systemic antibiotic use within 15 days prior to enrollment or for >10 days within the past 3 months; Professional dental prophylaxis or non-surgical periodontal therapy within the past 6 months; History of bleeding disorders; Same exclusion as parent study; Planning to receive or complete dental services during the 12-month course of the study; Ongoing orthodontic treatment.