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Effect of Ambient Temperature on Blood Glucose and Insulin Absorption in Adults With Type 1 Diabetes

Key facts

Where
Montreal, CanadaSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 45 years old?

Source: NCT07491133, who can take part

Where in Canada

  • Institut de Recherches Cliniques de MontrealMontreal, CanadaNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Institut de Recherches Cliniques de Montreal
Trial code
NCT07491133
Record updated
24 March 2026
Original description
The goal of this clinical trial is to learn how different temperatures affect blood sugar levels in adults with type 1 diabetes. Climate change is causing more extreme hot and cold weather, and people with type 1 diabetes may be at higher risk during these temperature changes. The main questions it aims to answer are:Read full original descriptionShow less

Effect of Ambient Temperature on Insulin Absorption and Change in Blood Glucose Levels in Individuals With Type 1 Diabetes

The goal of this clinical trial is to learn how different temperatures affect blood sugar levels in adults with type 1 diabetes. Climate change is causing more extreme hot and cold weather, and people with type 1 diabetes may be at higher risk during these temperature changes. The main questions it aims to answer are:

* Do different temperatures (cold, normal, or hot) change blood sugar levels in people with type 1 diabetes? * How does temperature affect insulin absorption in the body?

Researchers will compare three different temperature conditions to see how each affects blood sugar levels and insulin in the body.

Participants will:

* Complete a screening visit with body measurements and questionnaires * Attend 3 separate study visits, each in a different temperature setting: * Cold room (10°C/50°F) * Normal room temperature (23°C/73°F) * Hot and humid room (36°C/97°F with 65% humidity) * Sit for 2 hours in each temperature condition while researchers monitor their blood sugar, heart rate, and body temperature * Wear a continuous glucose monitor for 48-72 hours before each visit * Keep a diary of food, sleep, and activity for 24 hours before and after each visit

Each temperature visit is separated by at least 3 days. The study helps researchers understand if people with type 1 diabetes need special guidance for managing their blood sugar during extreme weather.

Inclusion: Diagnosis of type 1 diabetes for more than 2 years; Ability to provide verbal and written informed consent; Ability to speak and understand French.

Exclusion: Recent and/or unstable health condition (less than 3 months) prior to enrolment; Any viral infection at time of participation; Chronic illness other than type 1 diabetes (for example: pulmonary disease, cardiovascular disease, cancer); Health condition not controlled by medication; Any other health condition deemed to pose undue health risks during participation in the study; Pregnancy or breastfeeding (for female participants).

ClinicalTrials.gov NCT07491133