Guselkumab to Prevent Crohn's Disease Returning After Bowel Surgery
Follows adults with Crohn's disease treated with guselkumab after bowel surgery.
Plain-language title generated from the registry record
Registry title: An Observational, Multicenter Study to Evaluate the Effectiveness of Guselkumab for the Treatment of Participants With Crohn's Disease After Surgical Resection
Key facts
- Where
- Shanghai, ChinaSee the site
Where in China
- Shanghai 10th People's Hospital, Tongji University School of MedicineShanghai, ChinaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Shanghai 10th People's Hospital
- Trial code
- NCT07528040
- Record updated
- 14 April 2026
- Original description
The goal of this single arm ,non-interventional, prospective, descriptive study is to evaluate the efficacy of guselkumab treatment in preventing endoscopic recurrence of Crohn's Disease in adult participants who have a documented diagnosis of moderate to severe CD and have undergone an ileocolonic surgical resection. The primary endpoint is Endoscopic recurrence rate at week24.Read full original descriptionShow less
An Observational, Multicenter Study to Evaluate the Effectiveness of Guselkumab for the Treatment of Participants With Crohn's Disease After Surgical Resection
The goal of this single arm ,non-interventional, prospective, descriptive study is to evaluate the efficacy of guselkumab treatment in preventing endoscopic recurrence of Crohn's Disease in adult participants who have a documented diagnosis of moderate to severe CD and have undergone an ileocolonic surgical resection. The primary endpoint is Endoscopic recurrence rate at week24.
Inclusion: Patients≥ 18，; Have a documented diagnosis of moderate to severe CD; Have undergone an ileocolonic surgical resection.
Exclusion: Has complications of CD, such as short bowel syndrome Currently has or is suspected to have an abscess; Active infection; Currently has a malignancy or has a history of malignancy within 5 years.