Faster Pacemaker Heart Rate in People With Cardiac Amyloidosis
Tests a higher pacemaker rate in people with cardiac amyloidosis who already have pacemakers.
Plain-language title generated from the registry record
Registry title: Elevated Rate Pacing of Cardiac Amyloidosis
Key facts
- Where
- Minneapolis, United StatesSee the site
Where in United States
- University of MinnesotaMinneapolis, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Minnesota
- Trial code
- NCT07583823
- Record updated
- 13 October 2026
- Original description
This study aims to better quantify the improvements in heart failure symptoms and exercise tolerance before and after the heart rate elevation in a cohort of 10 cardiac amyloidosis patients with preexisting pacemakers.Read full original descriptionShow less
Elevated Rate Pacing of Cardiac Amyloidosis
This study aims to better quantify the improvements in heart failure symptoms and exercise tolerance before and after the heart rate elevation in a cohort of 10 cardiac amyloidosis patients with preexisting pacemakers.
Inclusion: Adults 18 and older; Diagnosis of cardiac amyloidosis as indicated by the criteria set forth in guidelines such as in Kittleson et al: "2023 ACC Expert Consensus Decision Pathway on Comprehensive Multidisciplinary Care for the Patient With Cardiac Amyloidosis: A Report of the American College of Cardiology Solution Set Oversight Committee; Implanted Cardiac Pacemaker (+/- Defibrillator); Pacemaker mode of AAI or DDD if in sinus rhythm, VVI acceptable if permanent atrial fibrillation; Non-dilated left ventricle by echocardiography; Ability to provide written consent; English Speaking.
Exclusion: Paced QRS duration of >150 ms (indicator for pacing mediated dyssynchrony); Dilated left ventricle.