Virtual reality headset to teach mindfulness-based therapy to people with migraine
Tests a virtual reality headset teaching mindfulness therapy to adults with migraine.
Plain-language title generated from the registry record
Registry title: Using Virtual Reality to Teach Mindfulness to People With Migraine
Key facts
- Where
- Boston and Chestnut Hill, United StatesSee the 3 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07599228, who can take part
Where in United States
- Brigham and Womens HospitalBoston, United StatesNo longer taking part
- Brigham and Women's Health Care CenterChestnut Hill, United StatesNo longer taking part
- Brigham and Women's HospitalChestnut Hill, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Brigham and Women's Hospital
- Trial code
- NCT07599228
- Record updated
- 30 September 2026
- Original description
The aim of this clinical trial is to learn if people with migraine can learn a type of biobehavioral therapy called Acceptance and Commitment Therapy (ACT) by using a virtual reality headset. Researchers are studying if this type of mindfulness therapy helps to decrease migraine-related disability. Participants will be randomized to treatment as usual or active virtual reality groups for four weeks. Everyone will keep symptom diaries, complete surveys, attend two clinic visits, and have two blood draws.Read full original descriptionShow less
Migraine Intervention Using Reality-Assisted Guided Experience
The aim of this clinical trial is to learn if people with migraine can learn a type of biobehavioral therapy called Acceptance and Commitment Therapy (ACT) by using a virtual reality headset. Researchers are studying if this type of mindfulness therapy helps to decrease migraine-related disability. Participants will be randomized to treatment as usual or active virtual reality groups for four weeks. Everyone will keep symptom diaries, complete surveys, attend two clinic visits, and have two blood draws.
Inclusion: Adults aged 18-80; Diagnosed with episodic migraine and experience 4-10 migraine days/month; On a stable dose of CGRP mAb for three months prior; Satisfy 4 week run-in of 4-10 headaches/month; Not taking other preventive medications; Not pregnant, breastfeeding, or planning to become pregnant within study timeframe; Able and willing to use VR device; No history of significant psychiatric illness; Willing to comply with study procedures; English-speaking.
Exclusion: Medication overuse (>10 days/month); Active psychiatric or neurological comorbidities; Significant visual/hearing/mobility impairment affecting VR use; Vertigo/vestibular dysfunction; Pregnancy, breastfeeding or planning pregnancy within study timeframe.