Tests EVO756 for preventing migraine in adults
Tests EVO756 against placebo to prevent migraine in adults aged 18 to 64.
Plain-language title generated from the registry record
Registry title: Study of EVO756 in Adults With Migraine
Key facts
- Where
- Amherst, Ann Arbor, Asheville, Atlanta, Austin, Buena Park, Canton, Centerville, Chandler, Charleston, Crab Orchard, Dallas, Decatur, Denver, Farmington Hills, Foxborough, Franklin, Fresno, Houston, Jacksonville, La Jolla, Los Angeles, McLean, Miami, New Haven, Orlando, Papillion, Raleigh, Stamford, Tampa, Toms River, Walnut Creek, West Palm Beach, and Westborough, United StatesSee the 37 sites
- Phase
- Phase 2
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 64 years old?
Source: NCT07616128, who can take part
Where in United States
- Clinosis - Dent Neurologic InstiteAmherst, United StatesTaking people
- Michigan Headache and Neurological InstituteAnn Arbor, United StatesTaking people
- Asheville Neurology Specialists PAAsheville, United StatesTaking people
- Clinical Integrative Research Center of AtlantaAtlanta, United StatesTaking people
- FutureSearch Trials of NeurologyAustin, United StatesTaking people
- Buena Park Research CenterBuena Park, United StatesNo longer taking part
- NeuroScience Research CenterCanton, United StatesTaking people
- Dayton Center for Neurological DisordersCenterville, United StatesTaking people
- TrialSphere CorpChandler, United StatesTaking people
- Clinical Trials of South CarolinaCharleston, United StatesTaking people
- Vaught Neurological ServicesCrab Orchard, United StatesTaking people
- FutureSearch Trials of DallasDallas, United StatesTaking people
- Accel Research Site-Decatur-AlcanzaDecatur, United StatesTaking people
- Denver Neurological ClinicDenver, United StatesTaking people
- Quest Research Institute - AlcanzaFarmington Hills, United StatesTaking people
- Neurology Center of New England P.C.Foxborough, United StatesTaking people
- Campbell Clinical ResearchFranklin, United StatesTaking people
- Neuro Pain Research CenterFresno, United StatesTaking people
- Mercury Clinical Research Inc. - Houston Neurology AssociatesHouston, United StatesTaking people
- SFF Medical Research Group LLCHouston, United StatesTaking people
- Clinical NeuroScience Solutions IncJacksonville, United StatesNo longer taking part
- Salma Health La JollaLa Jolla, United StatesTaking people
- CA Medical Clinic for HeadacheLos Angeles, United StatesTaking people
- MedStar Health: Headache Center at McLeanMcLean, United StatesTaking people
- Apple Medical Research Group, IncMiami, United StatesTaking people
- Blessed Healthcase & ResearchMiami, United StatesTaking people
- Florida Research Center, Inc.Miami, United StatesTaking people
- Hasbani NeurologyNew Haven, United StatesTaking people
- Clinical Neuroscience Solutions, Inc.Orlando, United StatesTaking people
- Papillion Research Center - Avacare Clinical ResearchPapillion, United StatesTaking people
- Eximia Research NCRaleigh, United StatesTaking people
- New England Institute for Neurology and HeadacheStamford, United StatesTaking people
- Vantage Clinical TrialsTampa, United StatesTaking people
- Bio Behavoural healthToms River, United StatesTaking people
- Diablo Clinical Research dba Flourish ResearchWalnut Creek, United StatesTaking people
- Premiere Research Institute at Palm Beach NeurologyWest Palm Beach, United StatesTaking people
- Mass Institute of Clinical ResearchWestborough, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Evommune, Inc.
- Trial code
- NCT07616128
- Record updated
- 4 November 2026
- Original description
This study will evaluate the efficacy and safety of EVO756 against placebo in adults with migraine.Read full original descriptionShow less
A Randomized, Double-Blind, Placebo Controlled Study Evaluating the Efficacy and Safety of EVO756 for the Prevention of Migraine in Adults
This study will evaluate the efficacy and safety of EVO756 against placebo in adults with migraine.
Inclusion: Adults aged 18 to <65 years; Migraine with or without aura, per ICHD-3 criteria; History of failure with prior preventive migraine treatments; Not currently using migraine preventive therapy.
Exclusion: Use of certain medications; Difficulty distinguishing migraine from other headache types or presence of other primary headache disorders; Any clinically significant medical, psychiatric, neurological, cardiovascular, or laboratory abnormalities.