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Looking at Tiny Plastic Particles in People With Crohn's Disease

Studies how tiny plastic particles relate to gut health in adults with Crohn's disease.

Plain-language title generated from the registry record
Registry title: A Pilot Study: Micro and NanoPlastics in Association With Crohn's Disease

Key facts

Where
Hong Kong, Hong KongSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 80 years old?

Source: NCT07630883, who can take part

Where in Hong Kong

  • Prince of Wales HospitalHong Kong, Hong KongNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Mak Wing Yan
Trial code
NCT07630883
Record updated
5 June 2026
Original description
Micro and nanoplastics (MNPs) are environmental contaminants found in food and water. Recent evidence suggests these particles may be linked to intestinal inflammation and changes in gut bacteria, which are key features of Crohn's Disease (CD). This study aims to investigate if patients with Crohn's Disease have a reduced ability to clear these plastic particles and how this affects their immune system and intestinal health.Read full original descriptionShow less

Integrated Multi-phase Investigation of Role of Micro and NanoPlastics in Association With Crohn's Disease: Targeting Microbiome, Immunity, and Barrier Dysfunction: A Pilot Study

Micro and nanoplastics (MNPs) are environmental contaminants found in food and water. Recent evidence suggests these particles may be linked to intestinal inflammation and changes in gut bacteria, which are key features of Crohn's Disease (CD). This study aims to investigate if patients with Crohn's Disease have a reduced ability to clear these plastic particles and how this affects their immune system and intestinal health.

Inclusion: Cases:; Age 18-80 years; Confirmed diagnosis of Crohn's disease (for cases); Ability to provide informed consent; Control:; Age 18-80 years old; No history of major large bowel resection; Ability to provide informed consent.

Exclusion: History of gastrointestinal malignancy; Advanced terminal medical illness, e.g. terminal malignancies; end staged renal failure and liver failure; Control:; Advanced terminal medical illness, e.g. terminal malignancies; end staged renal failure and liver failure; Cases:; Antibiotic/probiotic use within 4 weeks; Presence of stoma; Currently Pregnant; Currently Pregnant; Inability in giving consent.

ClinicalTrials.gov NCT07630883