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Skills training with brain-exercise practice for older adults with schizophrenia

Tests a combined skills and thinking training in older adults with schizophrenia.

Plain-language title generated from the registry record
Registry title: Optimizing CBSST With Executive Function Training for Schizophrenia (R33)

Key facts

Where
Dallas and San Diego, United StatesSee the 2 sites

Where in United States

  • UT Southwestern Medical CenterDallas, United StatesNo longer taking part
  • University of California San DiegoSan Diego, United StatesNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
University of California, San Diego
Trial code
NCT07658391
Record updated
23 June 2026
Original description
This randomized controlled clinical trial will test a blended intervention that combines Executive Function Training with Cognitive-Behavioral Skills Training (E-CBSST). E-CBSST will be delivered to adults with late-life schizophrenia to determine if it increases Cognitive Behavioral Social Skills Training skills learning more than a supportive contact control condition and leads to improved functioning.Read full original descriptionShow less

Optimizing Cognitive Behavioral Social Skills Training With Executive Function Training for Older Adults With Schizophrenia

This randomized controlled clinical trial will test a blended intervention that combines Executive Function Training with Cognitive-Behavioral Skills Training (E-CBSST). E-CBSST will be delivered to adults with late-life schizophrenia to determine if it increases Cognitive Behavioral Social Skills Training skills learning more than a supportive contact control condition and leads to improved functioning.

Inclusion: Voluntary informed consent to participate; Age 60 years or older; DSM-5 diagnosis of schizophrenia or schizoaffective disorder based on the SCID; Be clinically stable as operationalized by (1) not having been admitted to a psychiatric hospital within the three months prior to assessment, (2) having had no change in antipsychotic medication dosage within four weeks prior to the baseline assessment, and (3) and ascertained to be clinically and medically stable by one the study investigators; Be willing and able to speak English; Be able to read and converse (with corrected vision or hearing if needed).

Exclusion: Meets diagnostic criteria for bipolar disorder, current major depressive episode, or substance abuse or dependence within the six months prior to the baseline assessment except for caffeine or nicotine; Received electroconvulsive therapy within six months of the baseline assessment; Meets criteria for a cognitive disorder or for a neurological or other medical disorder affecting the ability to participate in Executive Function Training or CBSST.

ClinicalTrials.gov NCT07658391