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Omega-3 Fatty Acid Supplements for Blood Sugar in People With Type 2 Diabetes

Tests omega-3 fatty acid supplements in adults with type 2 diabetes.

Plain-language title generated from the registry record
Registry title: Free Fatty Acid Effects In Type 2 Diabetes

Key facts

Where
Coleraine, United KingdomSee the site

Where in United Kingdom

  • School of Biomedical SciencesColeraine, United KingdomNo longer taking part

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Trial details

Who runs it
University of Ulster
Trial code
NCT07677995
Record updated
1 September 2026
Original description
Omega-3 fatty acids are natural fats found in foods such as oily fish and flaxseed. Omega-3 fatty acids have been found to have positive effects on cardiovascular health, but there is less evidence on if they can help manage blood glucose in individuals with both cardiovascular disease and type 2 diabetes.Read full original descriptionShow less

Repositioning Omega-3 Fatty Acids For Treatment Of Glycaemia And Cardiometabolic Disease

Omega-3 fatty acids are natural fats found in foods such as oily fish and flaxseed. Omega-3 fatty acids have been found to have positive effects on cardiovascular health, but there is less evidence on if they can help manage blood glucose in individuals with both cardiovascular disease and type 2 diabetes.

This study will investigate whether the beneficial effects found in omega-3 fatty acids such as lowered blood glucose and reduced inflammation - both of which are important for managing type 2 diabetes and cardiovascular disease, can be beneficial for individuals with type 2 diabetes. As omega-3 fatty acids are already found naturally in food, and are already available as supplements, they could be a safe option to help manage these diseases.

The aim of this study is to investigate if omega-3 fatty acids can slow down the progression of type 2 diabetes and reduce the risk of cardiovascular disease in individuals with type 2 diabetes.

Inclusion: Individuals who are over 18 years of age with a BMI between 25-50 kg/m2, and who have been diagnosed with T2DM (>7.0 mmol/l fasting glucose) or pre-diabetes (impaired glucose tolerant 5.0-6.9mmol/l) and are either on no medication, are diet controlled or taking metformin. Participants may also have a history of cardiovascular disease.

Exclusion: Type 2 diabetics or prediabetics who are on an anti-diabetic medication (with the exception of metformin); Undergone recent major surgery or planned surgery during the study period; Those who have severe or unstable cardiovascular disease; Have an active infection; Have implanted devices (such as pacemakers or defibrillators); Are involved in any other type of weight loss study/intervention; Are pregnant/breastfeeding.

ClinicalTrials.gov NCT07677995