Type 2 diabetes trials in United Kingdom

In United Kingdom 60 Also abroad 1196

60 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Where
Airdrie, Birmingham, Chippenham, Glasgow, Leicester, London, Newcastle upon Tyne, Soham, Swansea
Age
18 years and over
People
2,000 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351045 · EU 2025-523104-71-00
Phase 3Taking people
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Where
Aberdeen, Antrim, Blackpool, Bristol, Dundee, Hounslow, Hull, Nuneaton, Plymouth, Taunton
Age
18 years and over
People
1,600 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351058 · EU 2025-523106-32-00
No phaseTaking people
Real-World Study of Patients With Type 1 Diabetes Treated With Teplizumab as Part of Managed Access Programs (MAPs)
Where
Birmingham, London
People
60 worldwide
Run by
Sanofi
See details and how to joinNCT07457580
Phase 3Taking people
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
Where
Airdrie, Chippenham, Hull, Llandough, Rotherham
Age
18 years and over
People
500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07776509 · EU 2025-523295-23-00
Phase 3Taking people
A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes
Where
Hull, Liverpool, London
Age
10 years to 17 years
People
170 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07668336 · EU 2025-524811-35-00
Phase 2Taking people
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Where
Birmingham, Blackpool, Bristol, Bromborough, Newcastle, Newquay, Nuneaton, Poole, Rotherham, Torpoint
Age
18 years to 75 years
People
200 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06897475 · EU 2024-520328-27-00
Phase 3Not yet taking people in United Kingdom
A Study of EloraTZP in Adult Participants With Obesity Without Type 2 Diabetes
Where
Blackpool, Lancashire, London, Penzance, Romsey, West Kirby
Age
18 years and over
People
2,115 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07881432 · EU 2026-526047-34-00
Phase 3Taking people
A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus
Where
Blackburn, Dundee, Guisborough, Nantwich, Rotherham, Thetford, Weston-super-Mare, Witney, Woodbridge, Yate
Age
18 years and over
People
2,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT07662109 · EU 2025-523941-81-00
Phase 3Taking people
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Where
Birmingham, Blackburn, Bournemouth, Bradford, Bristol, Bromborough, Chichester, Cosham, Darlington, Derby, Dundee, Falmouth, Guisborough, Ipswich, Kirkcaldy, Lancaster, Leeds, Lincoln, London, Manchester, Middlesbrough, Newcastle upon Tyne, Northallerton, Norwich, Southampton, Swansea, Trowbridge, Weymouth, York
Age
18 years and over
People
11,800 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07064473 · EU 2025-521188-11-00
Phase 3Taking people
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
Where
Chippenham, Corby, Dunfermline, Hull, Northwood
Age
18 years and over
People
1,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07784270
No phaseTaking people
GLycaemic Outcomes With Whey Protein in ageING
Where
Birmingham
Age
70 years to 90 years
People
32
Run by
University of Birmingham
See details and how to joinNCT07285811
Phase 3Taking people
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
Where
Aberdeen, Addlestone, Banbury, Bristol, Edinburgh, Hounslow, Penzance, Poole, Soham, Wansford, Yate
Age
18 years and over
People
1,200 worldwide
Run by
AstraZeneca
See details and how to joinNCT07662213 · EU 2025-523933-24-00
No phaseTaking people
A Multi-centre Trial to Assess the Efficacy and Safety of the Omnipod 5 System in People With Type 2 Diabetes Undergoing Haemodialysis
Where
Derby, London, Manchester
Age
18 years and over
People
84
Run by
Imperial College London
See details and how to joinNCT07422532
Phase 3Taking people
KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases
Where
London
Age
18 years and over
People
220 worldwide
Run by
Khondrion BV
See details and how to joinNCT06451757
Phase 3Taking people
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
Where
Ashton-under-Lyne, Blackpool, Chesterfield, Corby, Ely, Glasgow, Hounslow, Leicester, Metropolitan Borough of Wirral, Nantwich, Poole, Rotherham, Stowmarket, Wansford, Witney, Yate
Age
18 years and over
People
4,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07667803
Phase 3Taking people
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
Where
Birmingham
Age
18 years to 99 years
People
950 worldwide
Run by
Amgen
See details and how to joinNCT07684144 · EU 2025-524788-19-00
No phaseTaking people
Surveillance of Pancreatic Health After Diabetes Diagnosis
Where
Ashton-under-Lyne, Birmingham, Bournemouth, Brockham, Bromborough, Burton-on-Trent, Epsom, Kibworth Beauchamp, Kingswinford, Leek, Leicester, London, Maidstone, Manchester, Nottingham, Portsmouth, Rossendale, Ruislip, Sandbach, Southampton, Stratford-upon-Avon, Uttoxeter, Uxbridge, Walsall, Warlingham, Weymouth
Age
50 years to 84 years
People
5,000
Run by
University Hospital Southampton NHS Foundation Trust
See details and how to joinNCT06803771
No phaseTaking people
A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients Who Initiated Exenatide as Compared With Those Who Initiated Other Non-Glucagon-Like Peptide 1 Receptor Agonists Based Glucose Lowering Drugs
Where
Edinburgh, London
Age
18 years to 99 years
People
24,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT05663515
Phase 3Taking people
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
Where
Blackpool, Bradford on Avon, Lancashire, Lancaster, Londonderry, Manchester, Peterborough, Romsey, Torpoint
Age
18 years and over
People
1,980 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07321886 · EU 2025-523657-34-00
No phaseTaking people
Benefits of Retained Insulin for Good Health
Where
Bath, Bristol, Exeter, Truro
Age
18 years and over
People
700
Run by
Royal Devon and Exeter NHS Foundation Trust
See details and how to joinNCT07828626
Phase 3Taking people
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
Where
Cardiff, Edgbaston, Glasgow, London, Manchester, Stoke-on-Trent, Warrington
Age
18 years and over
People
1,560 worldwide
Run by
Ascletis Pharma (China) Co., Limited
See details and how to joinNCT07743450
Phase 4Taking people
A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK)
Where
Altrincham, Ashton-under-Lyne, Bolton, Bury, Cheshire, Great Lever, Hyde SK14, Manchester, Oldham, Rochdale, Sale, Salford, Stockport, Swinton, Wigen
Age
18 years and over
People
3,000
Run by
Eli Lilly and Company
See details and how to joinNCT07247084
Phase 3Taking people
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
Where
Blackpool, Glasgow, Hull, Penzance, Sandbach, Thetford, Whitney
Age
18 years and over
People
900 worldwide
Run by
AstraZeneca
See details and how to joinNCT07662135 · EU 2025-523940-12-00
Phase 3Taking people
A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
Where
Edinburgh, Headington, London, Newcastle upon Tyne
Age
18 years to 65 years
People
57 worldwide
Run by
Vertex Pharmaceuticals Incorporated
See details and how to joinNCT04786262 · EU 2024-513929-23-00
No phaseEnrolling by invitation
Free Fatty Acid Effects In Type 2 Diabetes
Where
Coleraine
Age
18 years and over
People
60
Run by
University of Ulster
See details and how to joinNCT07677995