Online lifestyle program to support weight loss in rural breast and endometrial cancer survivors
Tests an online lifestyle program for weight loss in rural breast and endometrial cancer survivors.
Plain-language title generated from the registry record
Registry title: Web-based Lifestyle Program, mHealth and EMA Intervention, to Improve Weight Loss in Rural Stage I-III Postmenopausal Breast and Endometrial Cancer Survivors, HERO-C Trial
Key facts
- Where
- Columbus, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 69 years old?
Source: NCT07723235, who can take part
Where in United States
- Ohio State University Comprehensive Cancer CenterColumbus, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Ohio State University Comprehensive Cancer Center
- Trial code
- NCT07723235
- Record updated
- 23 July 2026
- Original description
This clinical trial identifies the needs and preferences of rural stage I-III postmenopausal breast and endometrial cancer survivors and evaluates the impact of an adaptive, online program, mobile (m)Health + ecological momentary assessment (EMA) intervention, on lifestyle modification and their weight loss efforts. Obesity, a condition marked by an abnormally high, unhealthy amount of body fat, is associated with lower physical and psychological well-being, higher risk of recurrence, and higher cancer-specific and all-cause mortality (number of deaths). Lifestyle factors, such as low physical activity and unhealthy diet, are the main contributors to obesity that are modifiable. Lifestyle weight loss programs focusing on modifiable factors can improve cancer-specific survival and many aspects of health, but access to these programs can be challenging in rural settings. A remote lifestyle program, adapted to individual goals and needs, may help promote healthy behaviors, improve cancer outcomes, and reduce disease burden in stage I-III postmenopausal breast and endometrial cancer survivors.Read full original descriptionShow less
Health Engagement for Rural Ohio Cancer Survivors (HERO-C)
This clinical trial identifies the needs and preferences of rural stage I-III postmenopausal breast and endometrial cancer survivors and evaluates the impact of an adaptive, online program, mobile (m)Health + ecological momentary assessment (EMA) intervention, on lifestyle modification and their weight loss efforts. Obesity, a condition marked by an abnormally high, unhealthy amount of body fat, is associated with lower physical and psychological well-being, higher risk of recurrence, and higher cancer-specific and all-cause mortality (number of deaths). Lifestyle factors, such as low physical activity and unhealthy diet, are the main contributors to obesity that are modifiable. Lifestyle weight loss programs focusing on modifiable factors can improve cancer-specific survival and many aspects of health, but access to these programs can be challenging in rural settings. A remote lifestyle program, adapted to individual goals and needs, may help promote healthy behaviors, improve cancer outcomes, and reduce disease burden in stage I-III postmenopausal breast and endometrial cancer survivors.
Inclusion: Body mass index (BMI) ≥ 25kg/m\^2; Age: 40-69 years; 1-5 years post-diagnosis of stage I-III postmenopausal breast cancer or stage I-III endometrial cancer; No known evidence of recurrence (local or distant) or second, primary cancer; No prior history of new other malignancy since their breast or endometrial cancer diagnosis (other than non-melanoma skin cancer); Not currently participating in any weight loss programs, no personal trainer, and not meeting the physical activity guidelines; No use of any anti-obesity medications in the last 6 months and no plan to start anti-obesity medications during the study period; The ability to walk two blocks without a walker or cane; The ability to speak and read English; Have access to internet with a computer, tablet, or smart phone; Live in rural counties in Ohio and not planning to move away during the study; Are not pregnant, breastfeeding or less than 12-month post-partum and do not plan to become pregnant during the study.
Exclusion: Severe medical conditions, such as unstable cardiovascular disease or digestive disorders, that would preclude physical activity and dietary intervention; Lack of physician clearance if determined necessary by the Physical Activity Readiness Questionnaire (PAR-Q+); Acute physical limitations for unsupervised exercises at home; Unable to give informed consent.