Endometrial cancer trials in United States

In United States 199 Also abroad 395

199 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer
Where
Aurora, Centerville, Fort Lauderdale, Hilliard, Lexington, Los Angeles, Mineola, Minneapolis, Murray, New Haven, New York, Norfolk, Oklahoma City, Peoria, Reno, Shreveport, Sioux Falls, Syracuse, Tyler, Urbana, Washington D.C., Willow Grove
Age
18 years and over
People
480 worldwide
Run by
BioNTech SE
See details and how to joinNCT06340568 · EU 2023-507525-42-00
Phase 1Taking people
A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors
Where
Beverly Hills, Boston, Canton, Dallas, Denver, Durham, Hackensack, Little Rock, Nashville, New York, Omaha, Philadelphia, Portland, Providence
Age
18 years and over
People
156 worldwide
Run by
Context Therapeutics Inc.
See details and how to joinNCT06515613 · EU 2025-523968-20-00
Phase 3Taking people
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
Where
Albuquerque, Anchorage, Bethlehem, Boston, Centerville, Chattanooga, Chicago, Cincinnati, Columbus, Covington, Durham, Eugene, Fairfax, Fort Myers, Fort Wayne, Fort Worth, Gainesville, Houston, Irvine, Jackson, Kettering, Miami Beach, Mineola, Minneapolis, Mobile, New Haven, New York, Oklahoma City, Orange, Orlando, Philadelphia, Pinehurst, Pittsburgh, Providence, Reno, Richmond, San Antonio, Savannah, Scarborough, Shreveport, Solvang, St Louis, St. Petersburg, Teaneck, Tulsa, Tyler, Walnut Creek, Washington D.C., Webster, West Palm Beach
Age
18 years and over
People
1,123 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06952504 · EU 2024-519331-42-00
Phase 1/2Taking people
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
Where
Ann Arbor, Baltimore, Boston, Charlottesville, Fairfax, Houston, Los Angeles, Nashville, New York, Philadelphia, Salt Lake City, Seattle, St Louis
Age
18 years and over
People
616 worldwide
Run by
Verastem, Inc.
See details and how to joinNCT07020221
Phase 1Taking people
A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types
Where
Austin, Celebration, Denver, Detroit, Duarte, East Brunswick, Fairfax, Fort Worth, Houston, Irvine, Irving, Lake Success, Nashville, New Haven, New York, Plantation, San Antonio, Sarasota, Spokane, West Valley City
Age
18 years and over
People
150 worldwide
Run by
IDEAYA Biosciences
See details and how to joinNCT07503808 · EU 2026-526299-21-00
No phaseTaking people
Improving Rural Endometrial Cancer Care
Where
Chapel Hill
Age
18 years and over
People
50
Run by
UNC Lineberger Comprehensive Cancer Center
See details and how to joinNCT07927244
Phase 2Taking people
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer
Where
Bethesda
Age
18 years to 72 years
People
332
Run by
National Cancer Institute (NCI)
See details and how to joinNCT01174121
Phase 2Taking people
Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma
Where
Albuquerque, Anaconda, Ashland, Athens, Augusta, Battle Creek, Beachwood, Beaver, Billings, Birmingham, Boise, Bozeman, Buffalo, Butler, Caldwell, Carmel, Centerville, Chardon, Charlottesville, Chicago, Cincinnati, Cleveland, Coeur d'Alene, Columbia, Columbus, Coon Rapids, Cranberry Township, Crown Point, Dallas, Danville, Deer River, Duluth, Durham, Dyer, Edina, Edmonds, Effingham, Erie, Fargo, Farrell, Fort Worth, Fruitland, Grand Rapids, Great Falls, Greensburg, Hibbing, Hobart, Indiana, Indianapolis, Iowa City, Issaquah, Johnstown, Kalamazoo, Kalispell, Las Vegas, Louisville, Mattoon, Mayfield Heights, McKeesport, Mechanicsburg, Mentor, Meridian, Minneapolis, Missoula, Monroeville, Moon Township, Mount Pleasant, Munster, Muskegon, Nampa, Natrona Heights, New Castle, N. Huntingdon, Niles, Normal, Norton Shores, Oklahoma City, Omaha, Ontario, Parma, Pittsburgh, Portland, Post Falls, Providence, Raleigh, Reed City, Richardson, Richmond, Rochester, Saint Joseph, Saint Louis Park, Saint Paul, Sandpoint, Sandstone, Scarborough, Seattle, Seneca, Shakopee, St Louis, Syracuse, Traverse City, Tulsa, Urbana, Valparaiso, Virginia, Washington, Webster, Westlake, West Mifflin, Wyoming
Age
18 years and over
People
81
Run by
National Cancer Institute (NCI)
See details and how to joinNCT05112601
No phaseEnrolling by invitation
Developing a Gynecologic Cancer Health Promotion Community Engagement Program
Where
Philadelphia
Age
18 years and over
People
100
Run by
Abramson Cancer Center at Penn Medicine
See details and how to joinNCT07910162
Phase 3Taking people
Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer
Where
Augusta, Baltimore, Bel Air, Billings, Bryn Mawr, Butte, Carmel, Charlottesville, Chicago, Coral Gables, Dallas, Deerfield Beach, Detroit, Doral, Edina, Farmington Hills, Flint, Fort Worth, Houston, Indianapolis, Kearney, Las Vegas, Maple Grove, Maplewood, Marrero, Metairie, Miami, New Orleans, North Miami, Oklahoma City, Omaha, Paoli, Plantation, Princeton, Providence, Richardson, Saint Paul, Springfield, Sugar Land, The Woodlands, Warrenville, Washington D.C., Wynnewood, Wyoming
Age
18 years and over
People
428 worldwide
Run by
NRG Oncology
See details and how to joinNCT05646316
Phase 2Taking people
At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
Where
Grand Forks, Jacksonville
Age
18 years and over
People
220
Run by
Mayo Clinic
See details and how to joinNCT05969860
Phase 3Taking people
Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer
Where
‘Aiea, Albuquerque, Anaconda, Anchorage, Ankeny, Ann Arbor, Ashland, Athens, Atlanta, Augusta, Aurora, Baltimore, Basking Ridge, Battle Creek, Bay Shore, Beachwood, Bellevue, Billings, Birmingham, Boston, Bozeman, Brainerd, Brewer, Bridgeport, Brighton, Burlington, Camden, Canton, Carmichael, Carroll, Cedar Rapids, Chapel Hill, Chardon, Charleston, Charlottesville, Chelsea, Chicago, Cleveland, Clinton, Clive, Coeur d'Alene, Colorado Springs, Columbia, Columbus, Commack, Coon Rapids, Crown Point, Danville, Decatur, Deer River, DeKalb, Delaware, Des Moines, Detroit, Dublin, Duluth, Durham, Edina, Edmonds, Effingham, Elk Grove, Erie, Escanaba, Evanston, ‘Ewa Beach, Fargo, Farmington Hills, Fayetteville, Flint, Flushing, Fort Collins, Fort Dodge, Franklin, Fremont, Fresno, Geneva, Glenview, Goldsboro, Goshen, Grand Rapids, Great Falls, Greeley, Green Bay, Greenlawn, Greensburg, Harrison, Hartford, Harvey, Hershey, Hibbing, Highland Park, Highlands Ranch, Honolulu, Indianapolis, Iowa City, Issaquah, Jacksonville, Kalamazoo, Kalispell, Kearney, La Crosse, Lake Success, Lansing, Las Vegas, Lexington, Little Rock, Livingston, Livonia, Los Angeles, Loveland, Manchester, Manistique, Mansfield, Marion, Marrero, Martinsburg, Mattoon, Mechanicsburg, Mentor, Metairie, Middletown, Millville, Milwaukee, Minneapolis, Missoula, Modesto, Montvale, Morgantown, Muskegon, Nashville, Newark, New Britain, New Brunswick, New Lenox, New Orleans, New York, Niles, Normal, Norton Shores, N. Venice, Oak Brook, Oakland, Oak Park, Oconto Falls, O'Fallon, Oklahoma City, Omaha, Orland Park, Palo Alto, Paramus, Parkersburg, Parma, Peabody, Peoria, Philadelphia, Phoenix, Pickerington, Pittsburgh, Pontiac, Portland, Post Falls, Providence, Raleigh, Rancho Mirage, Reed City, Rego Park, Rehoboth Beach, Richmond, Ridgewood, Rochester, Rocklin, Rogers, Roseville, Sacramento, Saint Joseph, Saint Louis Park, Saint Paul, Salt Lake City, Sandpoint, Sandstone, San Francisco, San Jose, San Leandro, San Rafael, Santa Clara, Santa Rosa, Sarasota, Scarborough, Seattle, Sewell, Sheboygan, Sleepy Hollow, South Bend, South Jordan, South San Francisco, Spooner, Springdale, Springfield, Staten Island, St Louis, Stony Brook, Sturgeon Bay, Superior, Sylvania, Syracuse, The Bronx, Traverse City, Tualatin, Tucson, Uniondale, Urbana, Vallejo, Vancouver, Venice, Virginia, Walnut Creek, Warrenville, Washington, Washington D.C., Waukee, Webster, Westerville, Westlake, Willow Grove, Woodbury, Woodland, Wyoming, Ypsilanti
Age
18 years and over
People
255
Run by
National Cancer Institute (NCI)
See details and how to joinNCT07198074
No phaseTaking people
Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer
Where
Atlanta, Chicago, Cleveland, Detroit, Eau Claire, Evergreen Park, Grand Forks, Houston, Howard Beach, Jackson, Jacksonville, Katy, La Crosse, Miami, Milwaukee, New Orleans, Orlando, Pembroke Pines, Phoenix, Richmond, Rochester, Saginaw, Sarasota, Westbury
Age
18 years and over
People
3,110
Run by
Mayo Clinic
See details and how to joinNCT05051722
Phase 1/2Taking people
Pembrolizumab, Lenvatinib and IL-15 Superagonist N-803 in Combination With HER2 Targeting Autologous Dendritic Cell (AdHER2DC) Vaccine in Participants With Advanced or Metastatic Endometrial Cancer
Where
Bethesda
Age
18 years to 120 years
People
60
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06253494
Phase 1Taking people
A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors
Where
Atlanta, Augusta, Austin, Boston, Charlottesville, Dallas, Denver, Fairfax, Fairway, Hackensack, Lake Mary, Little Rock, Los Angeles, Nashville, Orlando, Philadelphia, Pittsburgh, Salt Lake City, San Francisco
Age
19 years and over
People
238 worldwide
Run by
NiKang Therapeutics, Inc.
See details and how to joinNCT06586957
Phase 3Taking people
Assessing Survival Outcomes With Checkpoint Inhibition ExteNded vs Discontinued in Endometrial Cancer
Where
Cary, Chapel Hill, Garner, Greensboro, Raleigh
Age
18 years and over
People
140
Run by
UNC Lineberger Comprehensive Cancer Center
See details and how to joinNCT07867002
Phase 2Taking people
Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors
Where
Allentown, Basking Ridge, Commack, Harrison, Hartford, Miami, Middletown, Montvale, New York, Uniondale
Age
18 years and over
People
212
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT04165772
No phaseTaking people
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
Where
Austin, Charleston, Cleveland, Corbin, Duarte, Elizabethtown, Florence, Gainesville, Lexington, Memphis, Miami, Minneapolis, Nashville, New Albany, Paducah, Portland, Rochester
Age
40 years and over
People
7,000
Run by
Adela, Inc
See details and how to joinNCT05366881
Phase 1/2Taking people
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
Where
Abilene, Augusta, Austin, Boston, Camden, Columbus, Dallas, Detroit, Doylestown, Eugene, Everett, Fairfax, Fort Myers, Fort Worth, Grand Rapids, Los Angeles, Maplewood, Nashville, Norfolk, Oklahoma City, Phoenix, Pittsburgh, Portland, Providence, Rockville, San Diego, Santa Barbara, Santa Rosa, St. Petersburg, Tucson, Tyler, West Palm Beach, West Valley City, Westwood, Woodland
Age
18 years and over
People
952 worldwide
Run by
Genmab
See details and how to joinNCT05579366
Phase 1Taking people
A Study of Sofe-M in Participants With Selected Advanced Solid Tumors
Where
Atlanta, Columbus, Falls Church, Grand Rapids, Houston, La Jolla, Mineola, New York, Scottsdale, West Valley City
Age
18 years and over
People
575 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06400472 · EU 2024-511238-11-00
Phase 2Taking people
A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors
Where
Amarillo, Chicago Ridge, Dallas, Detroit, Fort Myers, Horsham, Houston, Knoxville, Lake Success, Littleton, Nashville, New York, Orlando, Prescott, Roanoke, San Antonio, St. Petersburg, West Palm Beach, Westwood
Age
18 years and over
People
200 worldwide
Run by
Jazz Pharmaceuticals
See details and how to joinNCT06695845 · EU 2024-516551-41-00
Phase 2Taking people
A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Where
Birmingham, Boston, Cleveland, Detroit, Duarte, Farmington Hills, Fort Myers, Houston, Madison, Nashville, Seattle
Age
18 years and over
People
111 worldwide
Run by
Bayer
See details and how to joinNCT06760819 · EU 2024-517419-62-00
No phaseTaking people
Distance-Based Exercise to Preserve Function and Prevent Disability
Where
Boston, Butler, Cranberry Township, Dublin, Fremont, Fresno, Indiana, Kernersville, Mechanicsville, Midlothian, Modesto, Mount Airy, New Castle, Oakland, Pittsburgh, Richmond, Sacramento, San Francisco, San Jose, San Rafael, Santa Clara, Santa Rosa, Seneca, Vallejo, Walnut Creek, Winston-Salem
Age
18 years and over
People
104
Run by
Alliance for Clinical Trials in Oncology
See details and how to joinNCT07059884
Phase 1Taking people
Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors
Where
Canton, Charlotte, Dallas, Detroit, Durham, Fairfax, St Louis, West Valley City
Age
18 years and over
People
130 worldwide
Run by
Sairopa B.V.
See details and how to joinNCT05856981
No phaseTaking people
Molecular and ctDNA Characterization of High-Risk Endometrial Cancer
Where
Rochester
Age
18 years and over
People
100
Run by
Mayo Clinic
See details and how to joinNCT07062016